Stemmann O - Search Results

1

Positive and negative regulation of vertebrate separase by Cdk1-cyclin B1 may explain why securin is dispensable.

Hellmuth S, Pöhlmann C, Brown A, Böttger F, Sprinzl M, Stemmann O. Hellmuth S, et al. Among authors: stemmann o. J Biol Chem. 2015 Mar 20;290(12):8002-10. doi: 10.1074/jbc.M114.615310. Epub 2015 Feb 6. J Biol Chem. 2015. PMID: 25659430 Free PMC article.

2

Anaphase topsy-turvy: Cdk1 a securin, separase a CKI.

Stemmann O, Gorr IH, Boos D. Stemmann O, et al. Cell Cycle. 2006 Jan;5(1):11-3. doi: 10.4161/cc.5.1.2296. Epub 2006 Jan 4. Cell Cycle. 2006. PMID: 16340311 Review.

3

Essential CDK1-inhibitory role for separase during meiosis I in vertebrate oocytes.

Gorr IH, Reis A, Boos D, Wühr M, Madgwick S, Jones KT, Stemmann O. Gorr IH, et al. Among authors: stemmann o. Nat Cell Biol. 2006 Sep;8(9):1035-7. doi: 10.1038/ncb1467. Epub 2006 Aug 13. Nat Cell Biol. 2006. PMID: 16906143 Free PMC article.

4

Protein phosphatase 2A and separase form a complex regulated by separase autocleavage.

Holland AJ, Böttger F, Stemmann O, Taylor SS. Holland AJ, et al. Among authors: stemmann o. J Biol Chem. 2007 Aug 24;282(34):24623-32. doi: 10.1074/jbc.M702545200. Epub 2007 Jun 29. J Biol Chem. 2007. PMID: 17604273 Free article.

5

Phosphorylation-dependent binding of cyclin B1 to a Cdc6-like domain of human separase.

Boos D, Kuffer C, Lenobel R, Körner R, Stemmann O. Boos D, et al. Among authors: stemmann o. J Biol Chem. 2008 Jan 11;283(2):816-23. doi: 10.1074/jbc.M706748200. Epub 2007 Nov 1. J Biol Chem. 2008. PMID: 17974570 Free article.

6

Cyclin A2 is required for sister chromatid segregation, but not separase control, in mouse oocyte meiosis.

Touati SA, Cladière D, Lister LM, Leontiou I, Chambon JP, Rattani A, Böttger F, Stemmann O, Nasmyth K, Herbert M, Wassmann K. Touati SA, et al. Among authors: stemmann o. Cell Rep. 2012 Nov 29;2(5):1077-87. doi: 10.1016/j.celrep.2012.10.002. Epub 2012 Nov 1. Cell Rep. 2012. PMID: 23122964 Free article.

7

PP2A delays APC/C-dependent degradation of separase-associated but not free securin.

Hellmuth S, Böttger F, Pan C, Mann M, Stemmann O. Hellmuth S, et al. Among authors: stemmann o. EMBO J. 2014 May 16;33(10):1134-47. doi: 10.1002/embj.201488098. Epub 2014 Apr 29. EMBO J. 2014. PMID: 24781523 Free PMC article.

8

Human chromosome segregation involves multi-layered regulation of separase by the peptidyl-prolyl-isomerase Pin1.

Hellmuth S, Rata S, Brown A, Heidmann S, Novak B, Stemmann O. Hellmuth S, et al. Among authors: stemmann o. Mol Cell. 2015 May 7;58(3):495-506. doi: 10.1016/j.molcel.2015.03.025. Epub 2015 Apr 23. Mol Cell. 2015. PMID: 25921067 Free article.

9

Local activation of mammalian separase in interphase promotes double-strand break repair and prevents oncogenic transformation.

Hellmuth S, Gutiérrez-Caballero C, Llano E, Pendás AM, Stemmann O. Hellmuth S, et al. Among authors: stemmann o. EMBO J. 2018 Nov 15;37(22):e99184. doi: 10.15252/embj.201899184. Epub 2018 Oct 10. EMBO J. 2018. PMID: 30305303 Free PMC article.

10

Deletion of APC7 or APC16 Allows Proliferation of Human Cells without the Spindle Assembly Checkpoint.

Wild T, Budzowska M, Hellmuth S, Eibes S, Karemore G, Barisic M, Stemmann O, Choudhary C. Wild T, et al. Among authors: stemmann o. Cell Rep. 2018 Nov 27;25(9):2317-2328.e5. doi: 10.1016/j.celrep.2018.10.104. Cell Rep. 2018. PMID: 30485802 Free PMC article.

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