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Page 1
Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer.
Twyman-Saint Victor C, Rech AJ, Maity A, Rengan R, Pauken KE, Stelekati E, Benci JL, Xu B, Dada H, Odorizzi PM, Herati RS, Mansfield KD, Patsch D, Amaravadi RK, Schuchter LM, Ishwaran H, Mick R, Pryma DA, Xu X, Feldman MD, Gangadhar TC, Hahn SM, Wherry EJ, Vonderheide RH, Minn AJ. Twyman-Saint Victor C, et al. Among authors: patsch d. Nature. 2015 Apr 16;520(7547):373-7. doi: 10.1038/nature14292. Epub 2015 Mar 9. Nature. 2015. PMID: 25754329 Free PMC article.
A phase I trial of pembrolizumab with hypofractionated radiotherapy in patients with metastatic solid tumours.
Maity A, Mick R, Huang AC, George SM, Farwell MD, Lukens JN, Berman AT, Mitchell TC, Bauml J, Schuchter LM, O'Hara M, Lin LL, Demichele A, Christodouleas JP, Haas NB, Patsch DM, Hahn SM, Minn AJ, Wherry EJ, Vonderheide RH. Maity A, et al. Among authors: patsch dm. Br J Cancer. 2018 Nov;119(10):1200-1207. doi: 10.1038/s41416-018-0281-9. Epub 2018 Oct 15. Br J Cancer. 2018. PMID: 30318516 Free PMC article. Clinical Trial.
A stratified phase I dose escalation trial of hypofractionated radiotherapy followed by ipilimumab in metastatic melanoma: long-term follow-up and final outcomes.
Maity A, Mick R, Rengan R, Mitchell TC, Amaravadi RK, Schuchter LM, Pryma DA, Patsch DM, Maity AP, Minn AJ, Vonderheide RH, Lukens JN. Maity A, et al. Among authors: patsch dm. Oncoimmunology. 2021 Jan 31;10(1):1863631. doi: 10.1080/2162402X.2020.1863631. Oncoimmunology. 2021. PMID: 33643689 Free PMC article. Clinical Trial.
Clinical Outcomes of the HIV Protease Inhibitor Nelfinavir With Concurrent Chemoradiotherapy for Unresectable Stage IIIA/IIIB Non-Small Cell Lung Cancer: A Phase 1/2 Trial.
Rengan R, Mick R, Pryma DA, Lin LL, Christodouleas J, Plastaras JP, Simone CB 2nd, Gupta AK, Evans TL, Stevenson JP, Langer CJ, Kucharczuk J, Friedberg J, Lam S, Patsch D, Hahn SM, Maity A. Rengan R, et al. Among authors: patsch d. JAMA Oncol. 2019 Oct 1;5(10):1464-1472. doi: 10.1001/jamaoncol.2019.2095. JAMA Oncol. 2019. PMID: 31436839 Free PMC article.
Enriching productive mutational paths accelerates enzyme evolution.
Patsch D, Schwander T, Voss M, Schaub D, Hüppi S, Eichenberger M, Stockinger P, Schelbert L, Giger S, Peccati F, Jiménez-Osés G, Mutný M, Krause A, Bornscheuer UT, Hilvert D, Buller RM. Patsch D, et al. Nat Chem Biol. 2024 Dec;20(12):1662-1669. doi: 10.1038/s41589-024-01712-3. Epub 2024 Sep 11. Nat Chem Biol. 2024. PMID: 39261644 Free PMC article.
Improving Enzyme Fitness with Machine Learning.
Patsch D, Buller R. Patsch D, et al. Chimia (Aarau). 2023 Mar 29;77(3):116-121. doi: 10.2533/chimia.2023.116. Chimia (Aarau). 2023. PMID: 38047813 Free article. Review.
Asymmetric Cation-Olefin Monocyclization by Engineered Squalene-Hopene Cyclases.
Eichenberger M, Hüppi S, Patsch D, Aeberli N, Berweger R, Dossenbach S, Eichhorn E, Flachsmann F, Hortencio L, Voirol F, Vollenweider S, Bornscheuer UT, Buller R. Eichenberger M, et al. Among authors: patsch d. Angew Chem Int Ed Engl. 2021 Dec 6;60(50):26080-26086. doi: 10.1002/anie.202108037. Epub 2021 Sep 17. Angew Chem Int Ed Engl. 2021. PMID: 34346556 Free PMC article.
14 results