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Page 1
In vivo genome editing using Staphylococcus aureus Cas9.
Ran FA, Cong L, Yan WX, Scott DA, Gootenberg JS, Kriz AJ, Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F. Ran FA, et al. Among authors: sharp pa. Nature. 2015 Apr 9;520(7546):186-91. doi: 10.1038/nature14299. Epub 2015 Apr 1. Nature. 2015. PMID: 25830891 Free PMC article.
siRNA-directed inhibition of HIV-1 infection.
Novina CD, Murray MF, Dykxhoorn DM, Beresford PJ, Riess J, Lee SK, Collman RG, Lieberman J, Shankar P, Sharp PA. Novina CD, et al. Among authors: sharp pa. Nat Med. 2002 Jul;8(7):681-6. doi: 10.1038/nm725. Epub 2002 Jun 3. Nat Med. 2002. PMID: 12042777
14-3-3sigma controls mitotic translation to facilitate cytokinesis.
Wilker EW, van Vugt MA, Artim SA, Huang PH, Petersen CP, Reinhardt HC, Feng Y, Sharp PA, Sonenberg N, White FM, Yaffe MB. Wilker EW, et al. Among authors: sharp pa. Nature. 2007 Mar 15;446(7133):329-32. doi: 10.1038/nature05584. Nature. 2007. PMID: 17361185
MicroRNAs can generate thresholds in target gene expression.
Mukherji S, Ebert MS, Zheng GX, Tsang JS, Sharp PA, van Oudenaarden A. Mukherji S, et al. Among authors: sharp pa. Nat Genet. 2011 Aug 21;43(9):854-9. doi: 10.1038/ng.905. Nat Genet. 2011. PMID: 21857679 Free PMC article.
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.
Wu X, Scott DA, Kriz AJ, Chiu AC, Hsu PD, Dadon DB, Cheng AW, Trevino AE, Konermann S, Chen S, Jaenisch R, Zhang F, Sharp PA. Wu X, et al. Among authors: sharp pa. Nat Biotechnol. 2014 Jul;32(7):670-6. doi: 10.1038/nbt.2889. Epub 2014 Apr 20. Nat Biotechnol. 2014. PMID: 24752079 Free PMC article.
Global microRNA depletion suppresses tumor angiogenesis.
Chen S, Xue Y, Wu X, Le C, Bhutkar A, Bell EL, Zhang F, Langer R, Sharp PA. Chen S, et al. Among authors: sharp pa. Genes Dev. 2014 May 15;28(10):1054-67. doi: 10.1101/gad.239681.114. Epub 2014 May 1. Genes Dev. 2014. PMID: 24788094 Free PMC article.
CRISPR-mediated direct mutation of cancer genes in the mouse liver.
Xue W, Chen S, Yin H, Tammela T, Papagiannakopoulos T, Joshi NS, Cai W, Yang G, Bronson R, Crowley DG, Zhang F, Anderson DG, Sharp PA, Jacks T. Xue W, et al. Among authors: sharp pa. Nature. 2014 Oct 16;514(7522):380-4. doi: 10.1038/nature13589. Epub 2014 Aug 6. Nature. 2014. PMID: 25119044 Free PMC article.
512 results