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A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis.
Moriarity BS, Otto GM, Rahrmann EP, Rathe SK, Wolf NK, Weg MT, Manlove LA, LaRue RS, Temiz NA, Molyneux SD, Choi K, Holly KJ, Sarver AL, Scott MC, Forster CL, Modiano JF, Khanna C, Hewitt SM, Khokha R, Yang Y, Gorlick R, Dyer MA, Largaespada DA. Moriarity BS, et al. Among authors: largaespada da. Nat Genet. 2015 Jun;47(6):615-24. doi: 10.1038/ng.3293. Epub 2015 May 11. Nat Genet. 2015. PMID: 25961939 Free PMC article.
Transposon mutagenesis of the mouse germline.
Carlson CM, Dupuy AJ, Fritz S, Roberg-Perez KJ, Fletcher CF, Largaespada DA. Carlson CM, et al. Among authors: largaespada da. Genetics. 2003 Sep;165(1):243-56. doi: 10.1093/genetics/165.1.243. Genetics. 2003. PMID: 14504232 Free PMC article.
Target-site preferences of Sleeping Beauty transposons.
Liu G, Geurts AM, Yae K, Srinivasan AR, Fahrenkrug SC, Largaespada DA, Takeda J, Horie K, Olson WK, Hackett PB. Liu G, et al. Among authors: largaespada da. J Mol Biol. 2005 Feb 11;346(1):161-73. doi: 10.1016/j.jmb.2004.09.086. Epub 2004 Dec 30. J Mol Biol. 2005. PMID: 15663935
247 results