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Page 1
Strategies for shortening tuberculosis therapy.
Dartois VA, Mizrahi V, Savic RM, Silverman JA, Hermann D, Barry CE 3rd. Dartois VA, et al. Among authors: barry ce 3rd. Nat Med. 2025 Jun;31(6):1765-1775. doi: 10.1038/s41591-025-03742-3. Epub 2025 Jun 13. Nat Med. 2025. PMID: 40514466 Review.
Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of Mycobacterium tuberculosis.
Green SR, Harrison JR, Thompson S, Murugesan D, Libardo MDJ, Engelhart CA, Meshanni J, Fletcher D, Scullion P, Edwards D, Epemolu O, Mutter N, Shishikura Y, Riley J, Ioerger TR, Roca Guillén JJ, López LG, Read KD, Barry CE 3rd, Schnappinger D, Wyatt PG, Boshoff HIM, Cleghorn LAT. Green SR, et al. Among authors: barry ce 3rd. ACS Infect Dis. 2025 Mar 14;11(3):715-726. doi: 10.1021/acsinfecdis.4c00808. Epub 2025 Feb 27. ACS Infect Dis. 2025. PMID: 40014668 Free PMC article.
PET/CT guided tuberculosis treatment shortening: a randomized trial.
Malherbe ST, Chen RY, Yu X, Smith B, Liu X, Gao J, Diacon AH, Dawson R, Tameris M, Zhu H, Qu Y, Jin H, Pan S, Dodd LE, Wang J, Goldfeder LC, Cai Y, Arora K, Vincent J, Narunsky K, Serole K, Goliath RT, Da Costa L, Taliep A, Aziz S, Daroowala R, Thienemann F, Mukasa S, Court R, Sossen B, Ahlers P, Mendelsohn SC, White L, Gouel A, Lau CY, Hassan S, Liang L, Duan H, Moghaddam GK, Paripati P, Lahouar S, Harris M, Wollenberg K, Jeffrey B, Tartakovsky M, Rosenthal A, Duvenhage M, Armstrong DT, Song T, Winter J, Gao Q, Via LE, Wilkinson RJ, Walzl G, Barry CE 3rd. Malherbe ST, et al. Among authors: barry ce 3rd. medRxiv [Preprint]. 2024 Oct 4:2024.10.03.24314723. doi: 10.1101/2024.10.03.24314723. medRxiv. 2024. PMID: 39802795 Free PMC article. Preprint.
Leveraging insights from cancer to improve tuberculosis therapy.
Datta M, Via LE, Dartois V, Xu L, Barry CE 3rd, Jain RK. Datta M, et al. Among authors: barry ce 3rd. Trends Mol Med. 2025 Jan;31(1):11-20. doi: 10.1016/j.molmed.2024.07.011. Epub 2024 Aug 13. Trends Mol Med. 2025. PMID: 39142973 Free article.
Distributable, metabolic PET reporting of tuberculosis.
Khan RMN, Ahn YM, Marriner GA, Via LE, D'Hooge F, Seo Lee S, Yang N, Basuli F, White AG, Tomko JA, Frye LJ, Scanga CA, Weiner DM, Sutphen ML, Schimel DM, Dayao E, Piazza MK, Gomez F, Dieckmann W, Herscovitch P, Mason NS, Swenson R, Kiesewetter DO, Backus KM, Geng Y, Raj R, Anthony DC, Flynn JL, Barry CE 3rd, Davis BG. Khan RMN, et al. Among authors: barry ce 3rd. Nat Commun. 2024 Jun 27;15(1):5239. doi: 10.1038/s41467-024-48691-6. Nat Commun. 2024. PMID: 38937448 Free PMC article.
Mtb-Selective 5-Aminomethyl Oxazolidinone Prodrugs: Robust Potency and Potential Liabilities.
Boshoff HIM, Young K, Ahn YM, Yadav VD, Crowley BM, Yang L, Su J, Oh S, Arora K, Andrews J, Manikkam M, Sutphin M, Smith AJ, Weiner DM, Piazza MK, Fleegle JD, Gomez F, Dayao EK, Prideaux B, Zimmerman M, Kaya F, Sarathy J, Tan VY, Via LE, Tschirret-Guth R, Lenaerts AJ, Robertson GT, Dartois V, Olsen DB, Barry CE 3rd. Boshoff HIM, et al. Among authors: barry ce 3rd. ACS Infect Dis. 2024 May 10;10(5):1679-1695. doi: 10.1021/acsinfecdis.4c00025. Epub 2024 Apr 6. ACS Infect Dis. 2024. PMID: 38581700
Normalizing granuloma vasculature and matrix improves drug delivery and reduces bacterial burden in tuberculosis-infected rabbits.
Datta M, Via LE, Dartois V, Weiner DM, Zimmerman M, Kaya F, Walker AM, Fleegle JD, Raplee ID, McNinch C, Zarodniuk M, Kamoun WS, Yue C, Kumar AS, Subudhi S, Xu L, Barry CE 3rd, Jain RK. Datta M, et al. Among authors: barry ce 3rd. Proc Natl Acad Sci U S A. 2024 Apr 2;121(14):e2321336121. doi: 10.1073/pnas.2321336121. Epub 2024 Mar 26. Proc Natl Acad Sci U S A. 2024. PMID: 38530888 Free PMC article.
281 results