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Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
Kato N, Loh M, Takeuchi F, Verweij N, Wang X, Zhang W, Kelly TN, Saleheen D, Lehne B, Leach IM, Drong AW, Abbott J, Wahl S, Tan ST, Scott WR, Campanella G, Chadeau-Hyam M, Afzal U, Ahluwalia TS, Bonder MJ, Chen P, Dehghan A, Edwards TL, Esko T, Go MJ, Harris SE, Hartiala J, Kasela S, Kasturiratne A, Khor CC, Kleber ME, Li H, Yu Mok Z, Nakatochi M, Sapari NS, Saxena R, Stewart AFR, Stolk L, Tabara Y, Teh AL, Wu Y, Wu JY, Zhang Y, Aits I, Da Silva Couto Alves A, Das S, Dorajoo R, Hopewell JC, Kim YK, Koivula RW, Luan J, Lyytikäinen LP, Nguyen QN, Pereira MA, Postmus I, Raitakari OT, Scannell Bryan M, Scott RA, Sorice R, Tragante V, Traglia M, White J, Yamamoto K, Zhang Y, Adair LS, Ahmed A, Akiyama K, Asif R, Aung T, Barroso I, Bjonnes A, Braun TR, Cai H, Chang LC, Chen CH, Cheng CY, Chong YS, Collins R, Courtney R, Davies G, Delgado G, Do LD, Doevendans PA, Gansevoort RT, Gao YT, Grammer TB, Grarup N, Grewal J, Gu D, Wander GS, Hartikainen AL, Hazen SL, He J, Heng CK, Hixson JE, Hofman A, Hsu C, Huang W, Husemoen LLN, Hwang JY, Ichihara S, Igase M, Isono M, Justesen JM, Katsuya T, Kibriya MG, Kim YJ, Kishimoto M, Koh WP, Kohara K, Kumari M, Kwek K, Lee NR, Lee J, Liao J, Lieb W, Li… See abstract for full author list ➔ Kato N, et al. Among authors: turjanmaa v. Nat Genet. 2015 Nov;47(11):1282-1293. doi: 10.1038/ng.3405. Epub 2015 Sep 21. Nat Genet. 2015. PMID: 26390057 Free PMC article.
Interethnic analyses of blood pressure loci in populations of East Asian and European descent.
Takeuchi F, Akiyama M, Matoba N, Katsuya T, Nakatochi M, Tabara Y, Narita A, Saw WY, Moon S, Spracklen CN, Chai JF, Kim YJ, Zhang L, Wang C, Li H, Li H, Wu JY, Dorajoo R, Nierenberg JL, Wang YX, He J, Bennett DA, Takahashi A, Momozawa Y, Hirata M, Matsuda K, Rakugi H, Nakashima E, Isono M, Shirota M, Hozawa A, Ichihara S, Matsubara T, Yamamoto K, Kohara K, Igase M, Han S, Gordon-Larsen P, Huang W, Lee NR, Adair LS, Hwang MY, Lee J, Chee ML, Sabanayagam C, Zhao W, Liu J, Reilly DF, Sun L, Huo S, Edwards TL, Long J, Chang LC, Chen CH, Yuan JM, Koh WP, Friedlander Y, Kelly TN, Bin Wei W, Xu L, Cai H, Xiang YB, Lin K, Clarke R, Walters RG, Millwood IY, Li L, Chambers JC, Kooner JS, Elliott P, van der Harst P; International Genomics of Blood Pressure (iGEN-BP) Consortium; Chen Z, Sasaki M, Shu XO, Jonas JB, He J, Heng CK, Chen YT, Zheng W, Lin X, Teo YY, Tai ES, Cheng CY, Wong TY, Sim X, Mohlke KL, Yamamoto M, Kim BJ, Miki T, Nabika T, Yokota M, Kamatani Y, Kubo M, Kato N. Takeuchi F, et al. Nat Commun. 2018 Nov 28;9(1):5052. doi: 10.1038/s41467-018-07345-0. Nat Commun. 2018. PMID: 30487518 Free PMC article.
IL-18 gene polymorphism, cardiovascular mortality and coronary artery disease.
Hernesniemi JA, Anttila K, Nieminen T, Kähönen M, Mononen N, Nikus K, Turjanmaa V, Viik J, Lehtinen R, Lehtimäki T. Hernesniemi JA, et al. Among authors: turjanmaa v. Eur J Clin Invest. 2010 Nov;40(11):994-1001. doi: 10.1111/j.1365-2362.2010.02356.x. Eur J Clin Invest. 2010. PMID: 20735470
Combined assessment of heart rate recovery and T-wave alternans during routine exercise testing improves prediction of total and cardiovascular mortality: the Finnish Cardiovascular Study.
Leino J, Minkkinen M, Nieminen T, Lehtimäki T, Viik J, Lehtinen R, Nikus K, Kööbi T, Turjanmaa V, Verrier RL, Kähönen M. Leino J, et al. Among authors: turjanmaa v. Heart Rhythm. 2009 Dec;6(12):1765-71. doi: 10.1016/j.hrthm.2009.08.015. Epub 2009 Aug 14. Heart Rhythm. 2009. PMID: 19959127
Effect of common KCNE1 and SCN5A ion channel gene variants on T-wave alternans, a marker of cardiac repolarization, during clinical exercise stress test: the Finnish Cardiovascular Study.
Koskela J, Kähönen M, Fan M, Nieminen T, Lehtinen R, Viik J, Nikus K, Niemelä K, Kööbi T, Turjanmaa V, Pörsti I, Lehtimäki T. Koskela J, et al. Among authors: turjanmaa v. Transl Res. 2008 Aug;152(2):49-58. doi: 10.1016/j.trsl.2008.06.003. Epub 2008 Jul 23. Transl Res. 2008. PMID: 18674739 Clinical Trial.
114 results