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Page 1
Olorofim for the treatment of invasive fungal diseases in patients with few or no therapeutic options: a single-arm, open-label, phase 2b study.
Maertens JA, Thompson GR 3rd, Spec A, Donovan FM, Hammond SP, Bruns AHW, Rahav G, Shoham S, Johnson R, Rijnders B, Schaenman J, Hoenigl M, Morrissey CO, Mehta SR, Heath CH, Koehler P, Paterson DL, Slavin MA, Fortún J, Nguyen MH, Patterson TF, Uspenskaya O, Van de Veerdonk FL, Verweij PE, Aoun M, Georgala A, Alexander BD, Chayakulkeeree M, Mehra V, Miceli MH, Sikka MK, Solé A, Walsh TJ, Aguado JM, Holland SM, Moussa M, Rautemaa-Richardson R, Bazaz R, Schwartz S, Walsh SR, Plate M, Yehudai-Ofir D, Brüggemann RJ, Cornely OA, Ostrosky-Zeichner L, Vazquez JA, White PL, Cornelissen K, Ross GG, Fitton L, Dane A, Zinzi D, Rex JH, Chen SC. Maertens JA, et al. Among authors: plate m. Lancet Infect Dis. 2025 Jun 17:S1473-3099(25)00224-5. doi: 10.1016/S1473-3099(25)00224-5. Online ahead of print. Lancet Infect Dis. 2025. PMID: 40541222
Prenatal VEGF Nanodelivery Reverses Congenital Diaphragmatic Hernia-associated Pulmonary Abnormalities.
Loukogeorgakis SP, Michielin F, Al-Juffali N, Jimenez J, Shibuya S, Allen-Hyttinen J, Eastwood MP, Alhendi ASN, Davidson J, Naldi E, Maghsoudlou P, Tedeschi A, Khalaf S, Platé M, Fachin C, Dos Santos Dias A, Sindhwani N, Scaglioni D, Xenakis T, Sebire N, Giomo M, Eaton S, Toelen J, Luni C, Pavan P, Carmeliet P, Russo F, Janes S, Nikolić MZ, Elvassore N, Deprest J, De Coppi P. Loukogeorgakis SP, et al. Among authors: plate m. Am J Respir Crit Care Med. 2025 Jun;211(6):992-1006. doi: 10.1164/rccm.202401-0161OC. Am J Respir Crit Care Med. 2025. PMID: 39965074
Efficacy and Safety of Remdesivir in People With Impaired Kidney Function Hospitalized for COVID-19 Pneumonia: A Randomized Clinical Trial.
Sise ME, Santos JR, Goldman JD, Tuttle KR, Teixeira JP, Seibert AF, Koullias Y, Llewellyn J, Regan S, Zhao Y, Huang H, Hyland RH, Osinusi A, Winter H, Humeniuk R, Hulter HN, Gottlieb RL, Fusco DN, Birne R, Stancampiano FF, Libertin CR, Small CB, Plate M, McPhail MJ; REDPINE Investigators. Sise ME, et al. Among authors: plate m. Clin Infect Dis. 2024 Nov 22;79(5):1172-1181. doi: 10.1093/cid/ciae333. Clin Infect Dis. 2024. PMID: 38913574 Free PMC article. Clinical Trial.
Single-cell analysis of bronchoalveolar cells in inflammatory and fibrotic post-COVID lung disease.
Mehta P, Sanz-Magallón Duque de Estrada B, Denneny EK, Foster K, Turner CT, Mayer A, Milighetti M, Platé M, Worlock KB, Yoshida M, Brown JS, Nikolić MZ, Chain BM, Noursadeghi M, Chambers RC, Porter JC, Tomlinson GS. Mehta P, et al. Among authors: plate m. Front Immunol. 2024 May 17;15:1372658. doi: 10.3389/fimmu.2024.1372658. eCollection 2024. Front Immunol. 2024. PMID: 38827740 Free PMC article.
BTK drives neutrophil activation for sterilizing antifungal immunity.
Desai JV, Zarakas MA, Wishart AL, Roschewski M, Aufiero MA, Donkò A, Wigerblad G, Shlezinger N, Plate M, James MR, Lim JK, Uzel G, Bergerson JR, Fuss I, Cramer RA, Franco LM, Clark ES, Khan WN, Yamanaka D, Chamilos G, El-Benna J, Kaplan MJ, Staudt LM, Leto TL, Holland SM, Wilson WH, Hohl TM, Lionakis MS. Desai JV, et al. Among authors: plate m. J Clin Invest. 2024 May 2;134(12):e176142. doi: 10.1172/JCI176142. J Clin Invest. 2024. PMID: 38696257 Free PMC article.
Abatacept Pharmacokinetics and Exposure Response in Patients Hospitalized With COVID-19: A Secondary Analysis of the ACTIV-1 IM Randomized Clinical Trial.
Balevic SJ, Benjamin DK Jr, Powderly WG, Smith PB, Gonzalez D, McCarthy MW, Shaw LK, Lindsell CJ, Bozzette S, Williams D, Linas BP, Blamoun J, Javeri H, Hornik CP; ACTIV-1 IM Study Group. Balevic SJ, et al. JAMA Netw Open. 2024 Apr 1;7(4):e247615. doi: 10.1001/jamanetworkopen.2024.7615. JAMA Netw Open. 2024. PMID: 38662372 Free PMC article. Clinical Trial.
69 results