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Chromogranin A pathway: from pathogenic molecule to renal disease.
Mir SA, Biswas N, Cheung W, Wan J, Webster N, Macedo E, O'Connor DT, Vaingankar SM. Mir SA, et al. Among authors: vaingankar sm. J Hypertens. 2020 Mar;38(3):456-466. doi: 10.1097/HJH.0000000000002295. J Hypertens. 2020. PMID: 31714338 Free PMC article.
Catecholamine release-inhibitory peptide catestatin (chromogranin A(352-372)): naturally occurring amino acid variant Gly364Ser causes profound changes in human autonomic activity and alters risk for hypertension.
Rao F, Wen G, Gayen JR, Das M, Vaingankar SM, Rana BK, Mahata M, Kennedy BP, Salem RM, Stridsberg M, Abel K, Smith DW, Eskin E, Schork NJ, Hamilton BA, Ziegler MG, Mahata SK, O'Connor DT. Rao F, et al. Among authors: vaingankar sm. Circulation. 2007 May 1;115(17):2271-81. doi: 10.1161/CIRCULATIONAHA.106.628859. Epub 2007 Apr 16. Circulation. 2007. PMID: 17438154
Naturally occurring human genetic variation in the 3'-untranslated region of the secretory protein chromogranin A is associated with autonomic blood pressure regulation and hypertension in a sex-dependent fashion.
Chen Y, Rao F, Rodriguez-Flores JL, Mahata M, Fung MM, Stridsberg M, Vaingankar SM, Wen G, Salem RM, Das M, Cockburn MG, Schork NJ, Ziegler MG, Hamilton BA, Mahata SK, Taupenot L, O'Connor DT. Chen Y, et al. Among authors: vaingankar sm. J Am Coll Cardiol. 2008 Oct 28;52(18):1468-81. doi: 10.1016/j.jacc.2008.07.047. J Am Coll Cardiol. 2008. PMID: 19017515 Free PMC article.
Molecular Mechanism for Hypertensive Renal Disease: Differential Regulation of Chromogranin A Expression at 3'-Untranslated Region Polymorphism C+87T by MicroRNA-107.
Zhang K, Mir SA, Hightower CM, Miramontes-Gonzalez JP, Maihofer AX, Chen Y, Mahata SK, Nievergelt CM, Schork NJ, Freedman BI, Vaingankar SM, O'Connor DT. Zhang K, et al. Among authors: vaingankar sm. J Am Soc Nephrol. 2015 Aug;26(8):1816-25. doi: 10.1681/ASN.2014060537. Epub 2014 Nov 12. J Am Soc Nephrol. 2015. PMID: 25392232 Free PMC article.
40 results