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A phase I study afatinib/carboplatin/paclitaxel induction chemotherapy followed by standard chemoradiation in HPV-negative or high-risk HPV-positive locally advanced stage III/IVa/IVb head and neck squamous cell carcinoma.
Chung CH, Rudek MA, Kang H, Marur S, John P, Tsottles N, Bonerigo S, Veasey A, Kiess A, Quon H, Cmelak A, Murphy BA, Gilbert J. Chung CH, et al. Among authors: cmelak a. Oral Oncol. 2016 Feb;53:54-9. doi: 10.1016/j.oraloncology.2015.11.020. Epub 2015 Dec 17. Oral Oncol. 2016. PMID: 26705063 Free PMC article. Clinical Trial.
Gene expression profiles identify epithelial-to-mesenchymal transition and activation of nuclear factor-kappaB signaling as characteristics of a high-risk head and neck squamous cell carcinoma.
Chung CH, Parker JS, Ely K, Carter J, Yi Y, Murphy BA, Ang KK, El-Naggar AK, Zanation AM, Cmelak AJ, Levy S, Slebos RJ, Yarbrough WG. Chung CH, et al. Among authors: cmelak aj. Cancer Res. 2006 Aug 15;66(16):8210-8. doi: 10.1158/0008-5472.CAN-06-1213. Cancer Res. 2006. PMID: 16912200
Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas.
Chung CH, Ely K, McGavran L, Varella-Garcia M, Parker J, Parker N, Jarrett C, Carter J, Murphy BA, Netterville J, Burkey BB, Sinard R, Cmelak A, Levy S, Yarbrough WG, Slebos RJ, Hirsch FR. Chung CH, et al. Among authors: cmelak a. J Clin Oncol. 2006 Sep 1;24(25):4170-6. doi: 10.1200/JCO.2006.07.2587. J Clin Oncol. 2006. PMID: 16943533
A Phase II multi-institutional trial of chemoradiation using weekly docetaxel and erythropoietin for high-risk postoperative head and neck cancer patients.
Willey CD, Murphy BA, Netterville JL, Burkey BB, Shyr Y, Shakhtour B, Kish B, Raben D, Chen C, Song JI, Kane MA, Cmelak AJ. Willey CD, et al. Among authors: cmelak aj. Int J Radiat Oncol Biol Phys. 2007 Apr 1;67(5):1323-31. doi: 10.1016/j.ijrobp.2006.11.033. Epub 2007 Feb 7. Int J Radiat Oncol Biol Phys. 2007. PMID: 17289289 Clinical Trial.
Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer.
Posner MR, Hershock DM, Blajman CR, Mickiewicz E, Winquist E, Gorbounova V, Tjulandin S, Shin DM, Cullen K, Ervin TJ, Murphy BA, Raez LE, Cohen RB, Spaulding M, Tishler RB, Roth B, Viroglio Rdel C, Venkatesan V, Romanov I, Agarwala S, Harter KW, Dugan M, Cmelak A, Markoe AM, Read PW, Steinbrenner L, Colevas AD, Norris CM Jr, Haddad RI; TAX 324 Study Group. Posner MR, et al. Among authors: cmelak a. N Engl J Med. 2007 Oct 25;357(17):1705-15. doi: 10.1056/NEJMoa070956. N Engl J Med. 2007. PMID: 17960013 Free article. Clinical Trial.
120 results