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Reversible methylation of m6Am in the 5' cap controls mRNA stability.
Mauer J, Luo X, Blanjoie A, Jiao X, Grozhik AV, Patil DP, Linder B, Pickering BF, Vasseur JJ, Chen Q, Gross SS, Elemento O, Debart F, Kiledjian M, Jaffrey SR. Mauer J, et al. Among authors: gross ss. Nature. 2017 Jan 19;541(7637):371-375. doi: 10.1038/nature21022. Epub 2016 Dec 21. Nature. 2017. PMID: 28002401 Free PMC article.
FTO controls reversible m6Am RNA methylation during snRNA biogenesis.
Mauer J, Sindelar M, Despic V, Guez T, Hawley BR, Vasseur JJ, Rentmeister A, Gross SS, Pellizzoni L, Debart F, Goodarzi H, Jaffrey SR. Mauer J, et al. Among authors: gross ss. Nat Chem Biol. 2019 Apr;15(4):340-347. doi: 10.1038/s41589-019-0231-8. Epub 2019 Feb 18. Nat Chem Biol. 2019. PMID: 30778204 Free PMC article.
Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer's disease-like pathology.
Nuriel T, Angulo SL, Khan U, Ashok A, Chen Q, Figueroa HY, Emrani S, Liu L, Herman M, Barrett G, Savage V, Buitrago L, Cepeda-Prado E, Fung C, Goldberg E, Gross SS, Hussaini SA, Moreno H, Small SA, Duff KE. Nuriel T, et al. Among authors: gross ss. Nat Commun. 2017 Nov 13;8(1):1464. doi: 10.1038/s41467-017-01444-0. Nat Commun. 2017. PMID: 29133888 Free PMC article.
194 results