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Page 1
H255Y and K508R missense mutations in tumour suppressor folliculin (FLCN) promote kidney cell proliferation.
Hasumi H, Hasumi Y, Baba M, Nishi H, Furuya M, Vocke CD, Lang M, Irie N, Esumi C, Merino MJ, Kawahara T, Isono Y, Makiyama K, Warner AC, Haines DC, Wei MH, Zbar B, Hagenau H, Feigenbaum L, Kondo K, Nakaigawa N, Yao M, Metwalli AR, Marston Linehan W, Schmidt LS. Hasumi H, et al. Among authors: marston linehan w. Hum Mol Genet. 2017 Jan 15;26(2):354-366. doi: 10.1093/hmg/ddw392. Hum Mol Genet. 2017. PMID: 28007907 Free PMC article.
Lipid cell tumors in two women with von Hippel-Lindau syndrome.
Wagner M, Browne HN, Marston Linehan W, Merino M, Babar N, Stratton P. Wagner M, et al. Among authors: marston linehan w. Obstet Gynecol. 2010 Aug;116 Suppl 2(Suppl 2):535-539. doi: 10.1097/AOG.0b013e3181e25458. Obstet Gynecol. 2010. PMID: 20664446 Free PMC article.
Diagnosis and management of BHD-associated kidney cancer.
Stamatakis L, Metwalli AR, Middelton LA, Marston Linehan W. Stamatakis L, et al. Among authors: marston linehan w. Fam Cancer. 2013 Sep;12(3):397-402. doi: 10.1007/s10689-013-9657-4. Fam Cancer. 2013. PMID: 23703644 Free PMC article. Review.
Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation.
Hasumi Y, Baba M, Hasumi H, Huang Y, Lang M, Reindorf R, Oh HB, Sciarretta S, Nagashima K, Haines DC, Schneider MD, Adelstein RS, Schmidt LS, Sadoshima J, Marston Linehan W. Hasumi Y, et al. Among authors: marston linehan w. Hum Mol Genet. 2014 Nov 1;23(21):5706-19. doi: 10.1093/hmg/ddu286. Epub 2014 Jun 6. Hum Mol Genet. 2014. PMID: 24908670 Free PMC article.
The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding.
Woodford MR, Dunn DM, Blanden AR, Capriotti D, Loiselle D, Prodromou C, Panaretou B, Hughes PF, Smith A, Ackerman W, Haystead TA, Loh SN, Bourboulia D, Schmidt LS, Marston Linehan W, Bratslavsky G, Mollapour M. Woodford MR, et al. Among authors: marston linehan w. Nat Commun. 2016 Jun 29;7:12037. doi: 10.1038/ncomms12037. Nat Commun. 2016. PMID: 27353360 Free PMC article.
Renal functional outcomes after robotic multiplex partial nephrectomy: the National Cancer Institute experience with robotic partial nephrectomy for 3 or more tumors in a single kidney.
Hankins RA, Walton-Diaz A, Truong H, Shih J, Bratslavsky G, Pinto PA, Marston Linehan W, Metwalli AR. Hankins RA, et al. Among authors: marston linehan w. Int Urol Nephrol. 2016 Nov;48(11):1817-1821. doi: 10.1007/s11255-016-1392-y. Epub 2016 Aug 11. Int Urol Nephrol. 2016. PMID: 27515314 Free PMC article.
Targeting loss of the Hippo signaling pathway in NF2-deficient papillary kidney cancers.
Sourbier C, Liao PJ, Ricketts CJ, Wei D, Yang Y, Baranes SM, Gibbs BK, Ohanjanian L, Spencer Krane L, Scroggins BT, Keith Killian J, Wei MH, Kijima T, Meltzer PS, Citrin DE, Neckers L, Vocke CD, Marston Linehan W. Sourbier C, et al. Among authors: marston linehan w. Oncotarget. 2018 Jan 10;9(12):10723-10733. doi: 10.18632/oncotarget.24112. eCollection 2018 Feb 13. Oncotarget. 2018. PMID: 29535838 Free PMC article.
Blood and lymphatic systems are segregated by the FLCN tumor suppressor.
Tai-Nagara I, Hasumi Y, Kusumoto D, Hasumi H, Okabe K, Ando T, Matsuzaki F, Itoh F, Saya H, Liu C, Li W, Mukouyama YS, Marston Linehan W, Liu X, Hirashima M, Suzuki Y, Funasaki S, Satou Y, Furuya M, Baba M, Kubota Y. Tai-Nagara I, et al. Among authors: marston linehan w. Nat Commun. 2020 Dec 9;11(1):6314. doi: 10.1038/s41467-020-20156-6. Nat Commun. 2020. PMID: 33298956 Free PMC article.
PRDM10 RCC: A Birt-Hogg-Dubé-like Syndrome Associated With Lipoma and Highly Penetrant, Aggressive Renal Tumors Morphologically Resembling Type 2 Papillary Renal Cell Carcinoma.
Schmidt LS, Vocke CD, Ricketts CJ, Blake Z, Choo KK, Nielsen D, Gautam R, Crooks DR, Reynolds KL, Krolus JL, Bashyal M, Karim B, Cowen EW, Malayeri AA, Merino MJ, Srinivasan R, Ball MW, Zbar B, Marston Linehan W. Schmidt LS, et al. Among authors: marston linehan w. Urology. 2023 Sep;179:58-70. doi: 10.1016/j.urology.2023.04.035. Epub 2023 Jun 16. Urology. 2023. PMID: 37331486 Free PMC article.
16 results