van Mil SWC - Search Results

1

Farnesoid X Receptor Activation Promotes Hepatic Amino Acid Catabolism and Ammonium Clearance in Mice.

Massafra V, Milona A, Vos HR, Ramos RJJ, Gerrits J, Willemsen ECL, Ramos Pittol JM, Ijssennagger N, Houweling M, Prinsen HCMT, Verhoeven-Duif NM, Burgering BMT, van Mil SWC. Massafra V, et al. Among authors: van mil swc. Gastroenterology. 2017 May;152(6):1462-1476.e10. doi: 10.1053/j.gastro.2017.01.014. Epub 2017 Jan 25. Gastroenterology. 2017. PMID: 28130067 Free article.

2

Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy.

Van Mil SW, Milona A, Dixon PH, Mullenbach R, Geenes VL, Chambers J, Shevchuk V, Moore GE, Lammert F, Glantz AG, Mattsson LA, Whittaker J, Parker MG, White R, Williamson C. Van Mil SW, et al. Gastroenterology. 2007 Aug;133(2):507-16. doi: 10.1053/j.gastro.2007.05.015. Epub 2007 May 23. Gastroenterology. 2007. PMID: 17681172

3

Intestinal detoxification limits the activation of hepatic pregnane X receptor by lithocholic acid.

Owen BM, Milona A, van Mil S, Clements P, Holder J, Boudjelal M, Cairns W, Parker M, White R, Williamson C. Owen BM, et al. Drug Metab Dispos. 2010 Jan;38(1):143-9. doi: 10.1124/dmd.109.029306. Drug Metab Dispos. 2010. PMID: 19797606 Free PMC article.

4

The normal mechanisms of pregnancy-induced liver growth are not maintained in mice lacking the bile acid sensor Fxr.

Milona A, Owen BM, van Mil S, Dormann D, Mataki C, Boudjelal M, Cairns W, Schoonjans K, Milligan S, Parker M, White R, Williamson C. Milona A, et al. Am J Physiol Gastrointest Liver Physiol. 2010 Feb;298(2):G151-8. doi: 10.1152/ajpgi.00336.2009. Epub 2009 Oct 8. Am J Physiol Gastrointest Liver Physiol. 2010. PMID: 19815629 Free PMC article.

5

Bile acids and their nuclear receptor FXR: Relevance for hepatobiliary and gastrointestinal disease.

Gadaleta RM, van Mil SW, Oldenburg B, Siersema PD, Klomp LW, van Erpecum KJ. Gadaleta RM, et al. Biochim Biophys Acta. 2010 Jul;1801(7):683-92. doi: 10.1016/j.bbalip.2010.04.006. Epub 2010 Apr 23. Biochim Biophys Acta. 2010. PMID: 20399894 Review.

6

Raised hepatic bile acid concentrations during pregnancy in mice are associated with reduced farnesoid X receptor function.

Milona A, Owen BM, Cobbold JF, Willemsen EC, Cox IJ, Boudjelal M, Cairns W, Schoonjans K, Taylor-Robinson SD, Klomp LW, Parker MG, White R, van Mil SW, Williamson C. Milona A, et al. Hepatology. 2010 Oct;52(4):1341-9. doi: 10.1002/hep.23849. Hepatology. 2010. PMID: 20842631

7

Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease.

Gadaleta RM, van Erpecum KJ, Oldenburg B, Willemsen EC, Renooij W, Murzilli S, Klomp LW, Siersema PD, Schipper ME, Danese S, Penna G, Laverny G, Adorini L, Moschetta A, van Mil SW. Gadaleta RM, et al. Gut. 2011 Apr;60(4):463-72. doi: 10.1136/gut.2010.212159. Epub 2011 Jan 17. Gut. 2011. PMID: 21242261

8

Activation of bile salt nuclear receptor FXR is repressed by pro-inflammatory cytokines activating NF-κB signaling in the intestine.

Gadaleta RM, Oldenburg B, Willemsen EC, Spit M, Murzilli S, Salvatore L, Klomp LW, Siersema PD, van Erpecum KJ, van Mil SW. Gadaleta RM, et al. Biochim Biophys Acta. 2011 Aug;1812(8):851-8. doi: 10.1016/j.bbadis.2011.04.005. Epub 2011 Apr 22. Biochim Biophys Acta. 2011. PMID: 21540105 Free article.

9

Farnesoid X receptor (FXR) activation and FXR genetic variation in inflammatory bowel disease.

Nijmeijer RM, Gadaleta RM, van Mil SW, van Bodegraven AA, Crusius JB, Dijkstra G, Hommes DW, de Jong DJ, Stokkers PC, Verspaget HW, Weersma RK, van der Woude CJ, Stapelbroek JM, Schipper ME, Wijmenga C, van Erpecum KJ, Oldenburg B; Dutch Initiative on Crohn, Colitis (ICC). Nijmeijer RM, et al. PLoS One. 2011;6(8):e23745. doi: 10.1371/journal.pone.0023745. Epub 2011 Aug 22. PLoS One. 2011. PMID: 21887309 Free PMC article.

10

Anti-inflammatory and metabolic actions of FXR: insights into molecular mechanisms.

Hollman DA, Milona A, van Erpecum KJ, van Mil SW. Hollman DA, et al. Biochim Biophys Acta. 2012 Nov;1821(11):1443-52. doi: 10.1016/j.bbalip.2012.07.004. Epub 2012 Jul 20. Biochim Biophys Acta. 2012. PMID: 22820415 Review.

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