Cheng THT - Search Results

1

Genomewide bisulfite sequencing reveals the origin and time-dependent fragmentation of urinary cfDNA.

Cheng THT, Jiang P, Tam JCW, Sun X, Lee WS, Yu SCY, Teoh JYC, Chiu PKF, Ng CF, Chow KM, Szeto CC, Chan KCA, Chiu RWK, Lo YMD. Cheng THT, et al. Clin Biochem. 2017 Jun;50(9):496-501. doi: 10.1016/j.clinbiochem.2017.02.017. Epub 2017 Feb 24. Clin Biochem. 2017. PMID: 28238813 Free article. Clinical Trial.

2

DNase1 Does Not Appear to Play a Major Role in the Fragmentation of Plasma DNA in a Knockout Mouse Model.

Cheng THT, Lui KO, Peng XL, Cheng SH, Jiang P, Chan KCA, Chiu RWK, Lo YMD. Cheng THT, et al. Among authors: cheng sh. Clin Chem. 2018 Feb;64(2):406-408. doi: 10.1373/clinchem.2017.280446. Epub 2017 Nov 2. Clin Chem. 2018. PMID: 29097509 No abstract available.

3

Noninvasive Detection of Bladder Cancer by Shallow-Depth Genome-Wide Bisulfite Sequencing of Urinary Cell-Free DNA for Methylation and Copy Number Profiling.

Cheng THT, Jiang P, Teoh JYC, Heung MMS, Tam JCW, Sun X, Lee WS, Ni M, Chan RCK, Ng CF, Chan KCA, Chiu RWK, Lo YMD. Cheng THT, et al. Clin Chem. 2019 Jul;65(7):927-936. doi: 10.1373/clinchem.2018.301341. Epub 2019 Apr 15. Clin Chem. 2019. PMID: 30988170

4

Jagged Ends of Urinary Cell-Free DNA: Characterization and Feasibility Assessment in Bladder Cancer Detection.

Zhou Z, Cheng SH, Ding SC, Heung MMS, Xie T, Cheng THT, Lam WKJ, Peng W, Teoh JYC, Chiu PKF, Ng CF, Jiang P, Chan KCA, Chiu RWK, Lo YMD. Zhou Z, et al. Among authors: cheng tht. Clin Chem. 2021 Mar 31;67(4):621-630. doi: 10.1093/clinchem/hvaa325. Clin Chem. 2021. PMID: 33604652

5

Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin.

Sun K, Jiang P, Cheng SH, Cheng THT, Wong J, Wong VWS, Ng SSM, Ma BBY, Leung TY, Chan SL, Mok TSK, Lai PBS, Chan HLY, Sun H, Chan KCA, Chiu RWK, Lo YMD. Sun K, et al. Among authors: cheng tht. Genome Res. 2019 Mar;29(3):418-427. doi: 10.1101/gr.242719.118. Genome Res. 2019. PMID: 30808726 Free PMC article.

6

Preferred end coordinates and somatic variants as signatures of circulating tumor DNA associated with hepatocellular carcinoma.

Jiang P, Sun K, Tong YK, Cheng SH, Cheng THT, Heung MMS, Wong J, Wong VWS, Chan HLY, Chan KCA, Lo YMD, Chiu RWK. Jiang P, et al. Among authors: cheng tht, cheng sh. Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):E10925-E10933. doi: 10.1073/pnas.1814616115. Epub 2018 Oct 29. Proc Natl Acad Sci U S A. 2018. PMID: 30373822 Free PMC article.

7

Comprehensive characterization and resolution of discrepant spectrophotometric bilirubin results in patients on eltrombopag therapy.

Cheng THT, Tsui TKC, Kwok JSS, Lit LCW, Wong EYL, Kam RKT, Grote-Koska D, Staaden A, Okada H, Fuke N, Wong RSM, Li CK, Chan MHM. Cheng THT, et al. Clin Chem Lab Med. 2020 Sep 25;58(10):1713-1723. doi: 10.1515/cclm-2019-0684. Clin Chem Lab Med. 2020. PMID: 31584871 Free article.

8

A Targeted Gene Panel That Covers Coding, Non-coding and Short Tandem Repeat Regions Improves the Diagnosis of Patients With Neurodegenerative Diseases.

Yu AC, Yim AK, Chan AY, Yuen LYP, Au WC, Cheng THT, Lin X, Li JW, Chan LWL, Mok VCT, Chan TF, Chan HYE. Yu AC, et al. Among authors: cheng tht. Front Neurosci. 2019 Dec 11;13:1324. doi: 10.3389/fnins.2019.01324. eCollection 2019. Front Neurosci. 2019. PMID: 31920494 Free PMC article.

9

The implementation of genome sequencing in rare genetic diseases diagnosis: a pilot study from the Hong Kong genome project.

Lam WKJ, Lau CS, Luk HM, Au LWC, Chan GCP, Chan WYH, Cheng SSW, Cheng THT, Cheung LL, Cheung YF, Chong JSC, Chu ATW, Chung CCY, Chung KL, Fung CW, Fung ELW, Gao Y, Ho S, Hue SPY, Lee CH, Lee TL, Li PH, Lo HM, Man Lo IF, Loong HHF, Ma BM, Ma W, Pang SYY, Seto WK, Siu SWK, So H, Tam YH, Tang W, Wong RMS, Yap DYH, Yau MLY, Chung BHY, Lo SV; Hong Kong Genome Project. Lam WKJ, et al. Among authors: cheng tht. Lancet Reg Health West Pac. 2025 Jan 28;55:101473. doi: 10.1016/j.lanwpc.2025.101473. eCollection 2025 Feb. Lancet Reg Health West Pac. 2025. PMID: 39944418 Free PMC article.

10

Extending the phenotype of Shashi-Pena syndrome: a case report and review of literature.

Ho SKL, Cheng SSW, Cheng THT, Leung LT, Lam EKY, Mok MTS, Lo IFM, Luk HM. Ho SKL, et al. Among authors: cheng tht. Clin Dysmorphol. 2023 Jul 1;32(3):139-146. doi: 10.1097/MCD.0000000000000462. Epub 2023 May 12. Clin Dysmorphol. 2023. PMID: 37195319 Review. No abstract available.

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