Batchelor E - Search Results

1

NFκB Promotes Ovarian Tumorigenesis via Classical Pathways That Support Proliferative Cancer Cells and Alternative Pathways That Support ALDH⁺ Cancer Stem-like Cells.

House CD, Jordan E, Hernandez L, Ozaki M, James JM, Kim M, Kruhlak MJ, Batchelor E, Elloumi F, Cam MC, Annunziata CM. House CD, et al. Among authors: batchelor e. Cancer Res. 2017 Dec 15;77(24):6927-6940. doi: 10.1158/0008-5472.CAN-17-0366. Epub 2017 Oct 26. Cancer Res. 2017. PMID: 29074539 Free PMC article.

2

Protein stability of p53 targets determines their temporal expression dynamics in response to p53 pulsing.

Hanson RL, Porter JR, Batchelor E. Hanson RL, et al. Among authors: batchelor e. J Cell Biol. 2019 Apr 1;218(4):1282-1297. doi: 10.1083/jcb.201803063. Epub 2019 Feb 11. J Cell Biol. 2019. PMID: 30745421 Free PMC article.

3

p53 Pulses Diversify Target Gene Expression Dynamics in an mRNA Half-Life-Dependent Manner and Delineate Co-regulated Target Gene Subnetworks.

Porter JR, Fisher BE, Batchelor E. Porter JR, et al. Among authors: batchelor e. Cell Syst. 2016 Apr 27;2(4):272-82. doi: 10.1016/j.cels.2016.03.006. Epub 2016 Apr 7. Cell Syst. 2016. PMID: 27135539 Free PMC article.

4

Global Inhibition with Specific Activation: How p53 and MYC Redistribute the Transcriptome in the DNA Double-Strand Break Response.

Porter JR, Fisher BE, Baranello L, Liu JC, Kambach DM, Nie Z, Koh WS, Luo J, Stommel JM, Levens D, Batchelor E. Porter JR, et al. Among authors: batchelor e. Mol Cell. 2017 Sep 21;67(6):1013-1025.e9. doi: 10.1016/j.molcel.2017.07.028. Epub 2017 Aug 31. Mol Cell. 2017. PMID: 28867293 Free PMC article.

5

Far Upstream Element Binding Protein Plays a Crucial Role in Embryonic Development, Hematopoiesis, and Stabilizing Myc Expression Levels.

Zhou W, Chung YJ, Parrilla Castellar ER, Zheng Y, Chung HJ, Bandle R, Liu J, Tessarollo L, Batchelor E, Aplan PD, Levens D. Zhou W, et al. Among authors: batchelor e. Am J Pathol. 2016 Mar;186(3):701-15. doi: 10.1016/j.ajpath.2015.10.028. Epub 2016 Jan 14. Am J Pathol. 2016. PMID: 26774856 Free PMC article.

6

Disabled cell density sensing leads to dysregulated cholesterol synthesis in glioblastoma.

Kambach DM, Halim AS, Cauer AG, Sun Q, Tristan CA, Celiku O, Kesarwala AH, Shankavaram U, Batchelor E, Stommel JM. Kambach DM, et al. Among authors: batchelor e. Oncotarget. 2017 Feb 28;8(9):14860-14875. doi: 10.18632/oncotarget.14740. Oncotarget. 2017. PMID: 28118603 Free PMC article.

7

Determining the Limitations and Benefits of Noise in Gene Regulation and Signal Transduction through Single Cell, Microscopy-Based Analysis.

Harton MD, Batchelor E. Harton MD, et al. Among authors: batchelor e. J Mol Biol. 2017 Apr 21;429(8):1143-1154. doi: 10.1016/j.jmb.2017.03.007. Epub 2017 Mar 11. J Mol Biol. 2017. PMID: 28288800 Free PMC article. Review.

8

Tuning of mRNA stability through altering 3'-UTR sequences generates distinct output expression in a synthetic circuit driven by p53 oscillations.

Koh WS, Porter JR, Batchelor E. Koh WS, et al. Among authors: batchelor e. Sci Rep. 2019 Apr 12;9(1):5976. doi: 10.1038/s41598-019-42509-y. Sci Rep. 2019. PMID: 30979970 Free PMC article.

9

CRISPR/Cas9-mediated gene knockout is insensitive to target copy number but is dependent on guide RNA potency and Cas9/sgRNA threshold expression level.

Yuen G, Khan FJ, Gao S, Stommel JM, Batchelor E, Wu X, Luo J. Yuen G, et al. Among authors: batchelor e. Nucleic Acids Res. 2017 Nov 16;45(20):12039-12053. doi: 10.1093/nar/gkx843. Nucleic Acids Res. 2017. PMID: 29036671 Free PMC article.

10

Progress and challenges in understanding the regulation and function of p53 dynamics.

Yang Z, Hanson RL, Batchelor E. Yang Z, et al. Among authors: batchelor e. Biochem Soc Trans. 2021 Nov 1;49(5):2123-2131. doi: 10.1042/BST20210148. Biochem Soc Trans. 2021. PMID: 34495325 Free PMC article. Review.

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