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Targeting Multiple Effector Pathways in Pancreatic Ductal Adenocarcinoma with a G-Quadruplex-Binding Small Molecule.
Marchetti C, Zyner KG, Ohnmacht SA, Robson M, Haider SM, Morton JP, Marsico G, Vo T, Laughlin-Toth S, Ahmed AA, Di Vita G, Pazitna I, Gunaratnam M, Besser RJ, Andrade ACG, Diocou S, Pike JA, Tannahill D, Pedley RB, Evans TRJ, Wilson WD, Balasubramanian S, Neidle S. Marchetti C, et al. Among authors: pazitna i. J Med Chem. 2018 Mar 22;61(6):2500-2517. doi: 10.1021/acs.jmedchem.7b01781. Epub 2018 Feb 7. J Med Chem. 2018. PMID: 29356532 Free PMC article.
Discovery of new G-quadruplex binding chemotypes.
Ohnmacht SA, Varavipour E, Nanjunda R, Pazitna I, Di Vita G, Gunaratnam M, Kumar A, Ismail MA, Boykin DW, Wilson WD, Neidle S. Ohnmacht SA, et al. Among authors: pazitna i. Chem Commun (Camb). 2014 Jan 28;50(8):960-3. doi: 10.1039/c3cc48616h. Chem Commun (Camb). 2014. PMID: 24302123 Free PMC article.