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Flt-3L Expansion of Recipient CD8α+ Dendritic Cells Deletes Alloreactive Donor T Cells and Represents an Alternative to Posttransplant Cyclophosphamide for the Prevention of GVHD.
Markey KA, Kuns RD, Browne DJ, Gartlan KH, Robb RJ, Martins JP, Henden AS, Minnie SA, Cheong M, Koyama M, Smyth MJ, Steptoe RJ, Belz GT, Brocker T, Degli-Esposti MA, Lane SW, Hill GR. Markey KA, et al. Among authors: koyama m. Clin Cancer Res. 2018 Apr 1;24(7):1604-1616. doi: 10.1158/1078-0432.CCR-17-2148. Epub 2018 Jan 24. Clin Cancer Res. 2018. PMID: 29367429
Type I-IFNs control GVHD and GVL responses after transplantation.
Robb RJ, Kreijveld E, Kuns RD, Wilson YA, Olver SD, Don AL, Raffelt NC, De Weerd NA, Lineburg KE, Varelias A, Markey KA, Koyama M, Clouston AD, Hertzog PJ, Macdonald KP, Hill GR. Robb RJ, et al. Among authors: koyama m. Blood. 2011 Sep 22;118(12):3399-409. doi: 10.1182/blood-2010-12-325746. Epub 2011 Jun 30. Blood. 2011. PMID: 21719602 Free article.
Immune insufficiency during GVHD is due to defective antigen presentation within dendritic cell subsets.
Markey KA, Koyama M, Kuns RD, Lineburg KE, Wilson YA, Olver SD, Raffelt NC, Don AL, Varelias A, Robb RJ, Cheong M, Engwerda CR, Steptoe RJ, Ramshaw HS, Lopez AF, Vega-Ramos J, Lew AM, Villadangos JA, Hill GR, MacDonald KP. Markey KA, et al. Among authors: koyama m. Blood. 2012 Jun 14;119(24):5918-30. doi: 10.1182/blood-2011-12-398164. Epub 2012 Mar 13. Blood. 2012. PMID: 22415754 Free article.
Identification and expansion of highly suppressive CD8(+)FoxP3(+) regulatory T cells after experimental allogeneic bone marrow transplantation.
Robb RJ, Lineburg KE, Kuns RD, Wilson YA, Raffelt NC, Olver SD, Varelias A, Alexander KA, Teal BE, Sparwasser T, Hammerling GJ, Markey KA, Koyama M, Clouston AD, Engwerda CR, Hill GR, MacDonald KP. Robb RJ, et al. Among authors: koyama m. Blood. 2012 Jun 14;119(24):5898-908. doi: 10.1182/blood-2011-12-396119. Epub 2012 Apr 26. Blood. 2012. PMID: 22538855 Free article.
Promoting regulation via the inhibition of DNAM-1 after transplantation.
Koyama M, Kuns RD, Olver SD, Lineburg KE, Lor M, Teal BE, Raffelt NC, Leveque L, Chan CJ, Robb RJ, Markey KA, Alexander KA, Varelias A, Clouston AD, Smyth MJ, MacDonald KP, Hill GR. Koyama M, et al. Blood. 2013 Apr 25;121(17):3511-20. doi: 10.1182/blood-2012-07-444026. Epub 2013 Feb 21. Blood. 2013. PMID: 23430112 Free article.
Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo.
Zhang P, Tey SK, Koyama M, Kuns RD, Olver SD, Lineburg KE, Lor M, Teal BE, Raffelt NC, Raju J, Leveque L, Markey KA, Varelias A, Clouston AD, Lane SW, MacDonald KP, Hill GR. Zhang P, et al. Among authors: koyama m. J Immunol. 2013 Nov 15;191(10):5291-303. doi: 10.4049/jimmunol.1301181. Epub 2013 Oct 11. J Immunol. 2013. PMID: 24123683 Free article.
Cross-dressing by donor dendritic cells after allogeneic bone marrow transplantation contributes to formation of the immunological synapse and maximizes responses to indirectly presented antigen.
Markey KA, Koyama M, Gartlan KH, Leveque L, Kuns RD, Lineburg KE, Teal BE, MacDonald KP, Hill GR. Markey KA, et al. Among authors: koyama m. J Immunol. 2014 Jun 1;192(11):5426-33. doi: 10.4049/jimmunol.1302490. Epub 2014 Apr 30. J Immunol. 2014. PMID: 24790149 Free article.
CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease.
Alexander KA, Flynn R, Lineburg KE, Kuns RD, Teal BE, Olver SD, Lor M, Raffelt NC, Koyama M, Leveque L, Le Texier L, Melino M, Markey KA, Varelias A, Engwerda C, Serody JS, Janela B, Ginhoux F, Clouston AD, Blazar BR, Hill GR, MacDonald KP. Alexander KA, et al. Among authors: koyama m. J Clin Invest. 2014 Oct;124(10):4266-80. doi: 10.1172/JCI75935. Epub 2014 Aug 26. J Clin Invest. 2014. PMID: 25157821 Free PMC article.
1,176 results