Bloom JD - Search Results

1

Destabilized adaptive influenza variants critical for innate immune system escape are potentiated by host chaperones.

Phillips AM, Ponomarenko AI, Chen K, Ashenberg O, Miao J, McHugh SM, Butty VL, Whittaker CA, Moore CL, Bloom JD, Lin YS, Shoulders MD. Phillips AM, et al. Among authors: bloom jd. PLoS Biol. 2018 Sep 17;16(9):e3000008. doi: 10.1371/journal.pbio.3000008. eCollection 2018 Sep. PLoS Biol. 2018. PMID: 30222731 Free PMC article.

2

Mutational effects on stability are largely conserved during protein evolution.

Ashenberg O, Gong LI, Bloom JD. Ashenberg O, et al. Among authors: bloom jd. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21071-6. doi: 10.1073/pnas.1314781111. Epub 2013 Dec 9. Proc Natl Acad Sci U S A. 2013. PMID: 24324165 Free PMC article.

3

Site-Specific Amino Acid Preferences Are Mostly Conserved in Two Closely Related Protein Homologs.

Doud MB, Ashenberg O, Bloom JD. Doud MB, et al. Among authors: bloom jd. Mol Biol Evol. 2015 Nov;32(11):2944-60. doi: 10.1093/molbev/msv167. Epub 2015 Jul 29. Mol Biol Evol. 2015. PMID: 26226986 Free PMC article.

4

Cooperation between distinct viral variants promotes growth of H3N2 influenza in cell culture.

Xue KS, Hooper KA, Ollodart AR, Dingens AS, Bloom JD. Xue KS, et al. Among authors: bloom jd. Elife. 2016 Mar 15;5:e13974. doi: 10.7554/eLife.13974. Elife. 2016. PMID: 26978794 Free PMC article.

5

Deep mutational scanning identifies sites in influenza nucleoprotein that affect viral inhibition by MxA.

Ashenberg O, Padmakumar J, Doud MB, Bloom JD. Ashenberg O, et al. Among authors: bloom jd. PLoS Pathog. 2017 Mar 27;13(3):e1006288. doi: 10.1371/journal.ppat.1006288. eCollection 2017 Mar. PLoS Pathog. 2017. PMID: 28346537 Free PMC article.

6

Within-Host Evolution of Human Influenza Virus.

Xue KS, Moncla LH, Bedford T, Bloom JD. Xue KS, et al. Among authors: bloom jd. Trends Microbiol. 2018 Sep;26(9):781-793. doi: 10.1016/j.tim.2018.02.007. Epub 2018 Mar 10. Trends Microbiol. 2018. PMID: 29534854 Free PMC article. Review.

7

Enhanced ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin.

Phillips AM, Doud MB, Gonzalez LO, Butty VL, Lin YS, Bloom JD, Shoulders MD. Phillips AM, et al. Among authors: bloom jd. Elife. 2018 Sep 6;7:e38795. doi: 10.7554/eLife.38795. Elife. 2018. PMID: 30188321 Free PMC article.

8

Comprehensive mapping of adaptation of the avian influenza polymerase protein PB2 to humans.

Soh YS, Moncla LH, Eguia R, Bedford T, Bloom JD. Soh YS, et al. Among authors: bloom jd. Elife. 2019 Apr 30;8:e45079. doi: 10.7554/eLife.45079. Elife. 2019. PMID: 31038123 Free PMC article.

9

Compensatory epistasis maintains ACE2 affinity in SARS-CoV-2 Omicron BA.1.

Moulana A, Dupic T, Phillips AM, Chang J, Nieves S, Roffler AA, Greaney AJ, Starr TN, Bloom JD, Desai MM. Moulana A, et al. Among authors: bloom jd. Nat Commun. 2022 Nov 16;13(1):7011. doi: 10.1038/s41467-022-34506-z. Nat Commun. 2022. PMID: 36384919 Free PMC article.

10

The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution.

Moulana A, Dupic T, Phillips AM, Chang J, Roffler AA, Greaney AJ, Starr TN, Bloom JD, Desai MM. Moulana A, et al. Among authors: bloom jd. Elife. 2023 Feb 21;12:e83442. doi: 10.7554/eLife.83442. Elife. 2023. PMID: 36803543 Free PMC article.

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