Shehu AI - Search Results

1

CYP1A1 and 1B1-mediated metabolic pathways of dolutegravir, an HIV integrase inhibitor.

Zhu J, Wang P, Li F, Lu J, Shehu AI, Xie W, McMahon D, Ma X. Zhu J, et al. Among authors: shehu ai. Biochem Pharmacol. 2018 Dec;158:174-184. doi: 10.1016/j.bcp.2018.10.012. Epub 2018 Oct 17. Biochem Pharmacol. 2018. PMID: 30342022 Free PMC article.

2

Deficiency of N-acetyltransferase increases the interactions of isoniazid with endobiotics in mouse liver.

Wang P, Shehu AI, Lu J, Joshi RH, Venkataramanan R, Sugamori KS, Grant DM, Zhong XB, Ma X. Wang P, et al. Among authors: shehu ai. Biochem Pharmacol. 2017 Dec 1;145:218-225. doi: 10.1016/j.bcp.2017.09.001. Epub 2017 Sep 6. Biochem Pharmacol. 2017. PMID: 28888949 Free PMC article.

3

Liver metabolomics in a mouse model of erythropoietic protoporphyria.

Wang P, Sachar M, Guo GL, Shehu AI, Lu J, Zhong XB, Ma X. Wang P, et al. Among authors: shehu ai. Biochem Pharmacol. 2018 Aug;154:474-481. doi: 10.1016/j.bcp.2018.06.011. Epub 2018 Jun 12. Biochem Pharmacol. 2018. PMID: 29906468 Free PMC article.

4

ABCG2 Deficiency Does Not Alter Dolutegravir Metabolism and Pharmacokinetics.

Zhu J, Tian X, Shehu AI, McMahon DK, Ma X. Zhu J, et al. Among authors: shehu ai. J Pharmacol Exp Ther. 2020 Jul;374(1):38-43. doi: 10.1124/jpet.119.264424. Epub 2020 Apr 17. J Pharmacol Exp Ther. 2020. PMID: 32303561 Free PMC article.

5

The pregnane X receptor in tuberculosis therapeutics.

Shehu AI, Li G, Xie W, Ma X. Shehu AI, et al. Expert Opin Drug Metab Toxicol. 2016;12(1):21-30. doi: 10.1517/17425255.2016.1121381. Epub 2015 Dec 5. Expert Opin Drug Metab Toxicol. 2016. PMID: 26592418 Free PMC article. Review.

6

Biotransformation of Cobicistat: Metabolic Pathways and Enzymes.

Wang P, Shehu AI, Liu K, Lu J, Ma X. Wang P, et al. Among authors: shehu ai. Drug Metab Lett. 2016;10(2):111-23. doi: 10.2174/1872312810666160303112212. Drug Metab Lett. 2016. PMID: 26935921 Free PMC article.

7

The Opportunities of Metabolomics in Drug Safety Evaluation.

Wang P, Shehu AI, Ma X. Wang P, et al. Among authors: shehu ai. Curr Pharmacol Rep. 2017 Feb;3(1):10-15. doi: 10.1007/s40495-016-0079-5. Epub 2017 Jan 3. Curr Pharmacol Rep. 2017. PMID: 28758057 Free PMC article.

8

Identification of Novel Pathways in Idelalisib Metabolism and Bioactivation.

Zhu J, Wang P, Shehu AI, Lu J, Bi H, Ma X. Zhu J, et al. Among authors: shehu ai. Chem Res Toxicol. 2018 Jul 16;31(7):548-555. doi: 10.1021/acs.chemrestox.8b00023. Epub 2018 Jun 26. Chem Res Toxicol. 2018. PMID: 29896955 Free PMC article.

9

Pregnane X receptor activation potentiates ritonavir hepatotoxicity.

Shehu AI, Lu J, Wang P, Zhu J, Wang Y, Yang D, McMahon D, Xie W, Gonzalez FJ, Ma X. Shehu AI, et al. J Clin Invest. 2019 Apr 30;129(7):2898-2903. doi: 10.1172/JCI128274. J Clin Invest. 2019. PMID: 31039134 Free PMC article.

10

Enzymes and Pathways of Kavain Bioactivation and Biotransformation.

Wang P, Zhu J, Shehu AI, Lu J, Chen J, Zhong XB, Ma X. Wang P, et al. Among authors: shehu ai. Chem Res Toxicol. 2019 Jul 15;32(7):1335-1342. doi: 10.1021/acs.chemrestox.9b00098. Epub 2019 Jul 2. Chem Res Toxicol. 2019. PMID: 31265262

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