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Page 1
Revealing the cellular degradome by mass spectrometry analysis of proteasome-cleaved peptides.
Wolf-Levy H, Javitt A, Eisenberg-Lerner A, Kacen A, Ulman A, Sheban D, Dassa B, Fishbain-Yoskovitz V, Carmona-Rivera C, Kramer MP, Nudel N, Regev I, Zahavi L, Elinger D, Kaplan MJ, Morgenstern D, Levin Y, Merbl Y. Wolf-Levy H, et al. Among authors: kramer mp. Nat Biotechnol. 2018 Oct 22:10.1038/nbt.4279. doi: 10.1038/nbt.4279. Online ahead of print. Nat Biotechnol. 2018. PMID: 30346940 Free PMC article.
Golgi organization is regulated by proteasomal degradation.
Eisenberg-Lerner A, Benyair R, Hizkiahou N, Nudel N, Maor R, Kramer MP, Shmueli MD, Zigdon I, Cherniavsky Lev M, Ulman A, Sagiv JY, Dayan M, Dassa B, Rosenwald M, Shachar I, Li J, Wang Y, Dezorella N, Khan S, Porat Z, Shimoni E, Avinoam O, Merbl Y. Eisenberg-Lerner A, et al. Among authors: kramer mp. Nat Commun. 2020 Jan 21;11(1):409. doi: 10.1038/s41467-019-14038-9. Nat Commun. 2020. PMID: 31964869 Free PMC article.
Post-translational modifications reshape the antigenic landscape of the MHC I immunopeptidome in tumors.
Kacen A, Javitt A, Kramer MP, Morgenstern D, Tsaban T, Shmueli MD, Teo GC, da Veiga Leprevost F, Barnea E, Yu F, Admon A, Eisenbach L, Samuels Y, Schueler-Furman O, Levin Y, Nesvizhskii AI, Merbl Y. Kacen A, et al. Among authors: kramer mp. Nat Biotechnol. 2023 Feb;41(2):239-251. doi: 10.1038/s41587-022-01464-2. Epub 2022 Oct 6. Nat Biotechnol. 2023. PMID: 36203013 Free PMC article.
The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC.
Javitt A, Shmueli MD, Kramer MP, Kolodziejczyk AA, Cohen IJ, Radomir L, Sheban D, Kamer I, Litchfield K, Bab-Dinitz E, Zadok O, Neiens V, Ulman A, Wolf-Levy H, Eisenberg-Lerner A, Kacen A, Alon M, Rêgo AT, Stacher-Priehse E, Lindner M, Koch I, Bar J, Swanton C, Samuels Y, Levin Y, da Fonseca PCA, Elinav E, Friedman N, Meiners S, Merbl Y. Javitt A, et al. Among authors: kramer mp. Nat Cancer. 2023 May;4(5):629-647. doi: 10.1038/s43018-023-00557-4. Epub 2023 May 22. Nat Cancer. 2023. PMID: 37217651
Cell-autonomous innate immunity by proteasome-derived defence peptides.
Goldberg K, Lobov A, Antonello P, Shmueli MD, Yakir I, Weizman T, Ulman A, Sheban D, Laser E, Kramer MP, Shteinvil R, Chen G, Ibraheem A, Sysoeva V, Fishbain-Yoskovitz V, Mohapatra G, Abramov A, Shimshi S, Ogneva K, Nandy M, Amidror S, Bootz-Maoz H, Kuo SH, Dezorella N, Kacen A, Javitt A, Lau GW, Yissachar N, Hayouka Z, Merbl Y. Goldberg K, et al. Among authors: kramer mp. Nature. 2025 Mar;639(8056):1032-1041. doi: 10.1038/s41586-025-08615-w. Epub 2025 Mar 5. Nature. 2025. PMID: 40044870 Free PMC article.
Repurposing of glatiramer acetate to treat cardiac ischemia in rodent models.
Aviel G, Elkahal J, Umansky KB, Bueno-Levy H, Petrover Z, Kotlovski Y, Lendengolts D, Kain D, Shalit T, Zhang L, Miyara S, Kramer MP, Merbl Y, Kozlovski S, Alon R, Aharoni R, Arnon R, Mishali D, Katz U, Nachman D, Asleh R, Amir O, Tzahor E, Sarig R. Aviel G, et al. Among authors: kramer mp. Nat Cardiovasc Res. 2024 Sep;3(9):1049-1066. doi: 10.1038/s44161-024-00524-x. Epub 2024 Aug 26. Nat Cardiovasc Res. 2024. PMID: 39215106
CD74 is a novel transcription regulator.
Gil-Yarom N, Radomir L, Sever L, Kramer MP, Lewinsky H, Bornstein C, Blecher-Gonen R, Barnett-Itzhaki Z, Mirkin V, Friedlander G, Shvidel L, Herishanu Y, Lolis EJ, Becker-Herman S, Amit I, Shachar I. Gil-Yarom N, et al. Among authors: kramer mp. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):562-567. doi: 10.1073/pnas.1612195114. Epub 2016 Dec 28. Proc Natl Acad Sci U S A. 2017. PMID: 28031488 Free PMC article.
53 results