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Loss-of-function mutations in KIF14 cause severe microcephaly and kidney development defects in humans and zebrafish.
Reilly ML, Stokman MF, Magry V, Jeanpierre C, Alves M, Paydar M, Hellinga J, Delous M, Pouly D, Failler M, Martinovic J, Loeuillet L, Leroy B, Tantau J, Roume J, Gregory-Evans CY, Shan X, Filges I, Allingham JS, Kwok BH, Saunier S, Giles RH, Benmerah A. Reilly ML, et al. Among authors: allingham js. Hum Mol Genet. 2019 Mar 1;28(5):778-795. doi: 10.1093/hmg/ddy381. Hum Mol Genet. 2019. PMID: 30388224 Free PMC article.
KIF14 binds tightly to microtubules and adopts a rigor-like conformation.
Arora K, Talje L, Asenjo AB, Andersen P, Atchia K, Joshi M, Sosa H, Allingham JS, Kwok BH. Arora K, et al. Among authors: allingham js. J Mol Biol. 2014 Aug 26;426(17):2997-3015. doi: 10.1016/j.jmb.2014.05.030. Epub 2014 Jun 17. J Mol Biol. 2014. PMID: 24949858 Free article.
Conditional switching of KIF2A mutation provides new insights into cortical malformation pathogeny.
Gilet JG, Ivanova EL, Trofimova D, Rudolf G, Meziane H, Broix L, Drouot N, Courraud J, Skory V, Voulleminot P, Osipenko M, Bahi-Buisson N, Yalcin B, Birling MC, Hinckelmann MV, Kwok BH, Allingham JS, Chelly J. Gilet JG, et al. Among authors: allingham js. Hum Mol Genet. 2020 Mar 27;29(5):766-784. doi: 10.1093/hmg/ddz316. Hum Mol Genet. 2020. PMID: 31919497 Free PMC article.
These motors were made for walking.
Hunter B, Allingham JS. Hunter B, et al. Among authors: allingham js. Protein Sci. 2020 Aug;29(8):1707-1723. doi: 10.1002/pro.3895. Epub 2020 Jun 26. Protein Sci. 2020. PMID: 32472639 Free PMC article. Review.
48 results