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Single-Cell RNA Sequencing of Blood and Ileal T Cells From Patients With Crohn's Disease Reveals Tissue-Specific Characteristics and Drug Targets.
Uniken Venema WT, Voskuil MD, Vila AV, van der Vries G, Jansen BH, Jabri B, Faber KN, Dijkstra G, Xavier RJ, Wijmenga C, Graham DB, Weersma RK, Festen EA. Uniken Venema WT, et al. Among authors: graham db. Gastroenterology. 2019 Feb;156(3):812-815.e22. doi: 10.1053/j.gastro.2018.10.046. Epub 2018 Nov 2. Gastroenterology. 2019. PMID: 30391472 Free PMC article. No abstract available.
Novel mechanism of tumor suppression by polarity gene discs large 1 (DLG1) revealed in a murine model of pediatric B-ALL.
Sandoval GJ, Graham DB, Gmyrek GB, Akilesh HM, Fujikawa K, Sammut B, Bhattacharya D, Srivatsan S, Kim A, Shaw AS, Yang-Iott K, Bassing CH, Duncavage E, Xavier RJ, Swat W. Sandoval GJ, et al. Among authors: graham db. Cancer Immunol Res. 2013 Dec;1(6):426-37. doi: 10.1158/2326-6066.CIR-13-0065. Epub 2013 Oct 7. Cancer Immunol Res. 2013. PMID: 24778134 Free PMC article.
Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells.
Sundberg TB, Choi HG, Song JH, Russell CN, Hussain MM, Graham DB, Khor B, Gagnon J, O'Connell DJ, Narayan K, Dančík V, Perez JR, Reinecker HC, Gray NS, Schreiber SL, Xavier RJ, Shamji AF. Sundberg TB, et al. Among authors: graham db. Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12468-73. doi: 10.1073/pnas.1412308111. Epub 2014 Aug 11. Proc Natl Acad Sci U S A. 2014. PMID: 25114223 Free PMC article.
CRISPR-Cas9 knockin mice for genome editing and cancer modeling.
Platt RJ, Chen S, Zhou Y, Yim MJ, Swiech L, Kempton HR, Dahlman JE, Parnas O, Eisenhaure TM, Jovanovic M, Graham DB, Jhunjhunwala S, Heidenreich M, Xavier RJ, Langer R, Anderson DG, Hacohen N, Regev A, Feng G, Sharp PA, Zhang F. Platt RJ, et al. Among authors: graham db. Cell. 2014 Oct 9;159(2):440-55. doi: 10.1016/j.cell.2014.09.014. Epub 2014 Sep 25. Cell. 2014. PMID: 25263330 Free PMC article.
126 results