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CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline.
Suárez-Calvet M, Capell A, Araque Caballero MÁ, Morenas-Rodríguez E, Fellerer K, Franzmeier N, Kleinberger G, Eren E, Deming Y, Piccio L, Karch CM, Cruchaga C, Paumier K, Bateman RJ, Fagan AM, Morris JC, Levin J, Danek A, Jucker M, Masters CL, Rossor MN, Ringman JM, Shaw LM, Trojanowski JQ, Weiner M, Ewers M, Haass C; Dominantly Inherited Alzheimer Network; Alzheimer's Disease Neuroimaging Initiative. Suárez-Calvet M, et al. Among authors: levin j. EMBO Mol Med. 2018 Dec;10(12):e9712. doi: 10.15252/emmm.201809712. EMBO Mol Med. 2018. PMID: 30482868 Free PMC article.
Applied multimodal diagnostics in a case of presenile dementia.
Schönecker S, Brendel M, Huber M, Vollmar C, Huppertz HJ, Teipel S, Okamura N, Levin J, Rominger A, Danek A. Schönecker S, et al. Among authors: levin j. BMC Neurol. 2016 Aug 9;16:131. doi: 10.1186/s12883-016-0647-7. BMC Neurol. 2016. PMID: 27506761 Free PMC article.
Early changes in CSF sTREM2 in dominantly inherited Alzheimer's disease occur after amyloid deposition and neuronal injury.
Suárez-Calvet M, Araque Caballero MÁ, Kleinberger G, Bateman RJ, Fagan AM, Morris JC, Levin J, Danek A, Ewers M, Haass C; Dominantly Inherited Alzheimer Network. Suárez-Calvet M, et al. Among authors: levin j. Sci Transl Med. 2016 Dec 14;8(369):369ra178. doi: 10.1126/scitranslmed.aag1767. Sci Transl Med. 2016. PMID: 27974666 Free PMC article.
Poly-GP in cerebrospinal fluid links C9orf72-associated dipeptide repeat expression to the asymptomatic phase of ALS/FTD.
Lehmer C, Oeckl P, Weishaupt JH, Volk AE, Diehl-Schmid J, Schroeter ML, Lauer M, Kornhuber J, Levin J, Fassbender K, Landwehrmeyer B; German Consortium for Frontotemporal Lobar Degeneration; Schludi MH, Arzberger T, Kremmer E, Flatley A, Feederle R, Steinacker P, Weydt P, Ludolph AC, Edbauer D, Otto M. Lehmer C, et al. Among authors: levin j. EMBO Mol Med. 2017 Jul;9(7):859-868. doi: 10.15252/emmm.201607486. EMBO Mol Med. 2017. PMID: 28408402 Free PMC article.
Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer's disease.
Müller S, Preische O, Sohrabi HR, Gräber S, Jucker M, Dietzsch J, Ringman JM, Martins RN, McDade E, Schofield PR, Ghetti B, Rossor M, Graff-Radford NR, Levin J, Galasko D, Quaid KA, Salloway S, Xiong C, Benzinger T, Buckles V, Masters CL, Sperling R, Bateman RJ, Morris JC, Laske C. Müller S, et al. Among authors: levin j. Sci Rep. 2017 Apr 27;7(1):1225. doi: 10.1038/s41598-017-01327-w. Sci Rep. 2017. PMID: 28450713 Free PMC article.
2,333 results