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Page 1
Transcriptional Heterogeneity of Beta Cells in the Intact Pancreas.
Farack L, Golan M, Egozi A, Dezorella N, Bahar Halpern K, Ben-Moshe S, Garzilli I, Tóth B, Roitman L, Krizhanovsky V, Itzkovitz S. Farack L, et al. Among authors: krizhanovsky v. Dev Cell. 2019 Jan 7;48(1):115-125.e4. doi: 10.1016/j.devcel.2018.11.001. Epub 2018 Nov 29. Dev Cell. 2019. PMID: 30503750 Free article.
Quantitative identification of senescent cells in aging and disease.
Biran A, Zada L, Abou Karam P, Vadai E, Roitman L, Ovadya Y, Porat Z, Krizhanovsky V. Biran A, et al. Among authors: krizhanovsky v. Aging Cell. 2017 Aug;16(4):661-671. doi: 10.1111/acel.12592. Epub 2017 Apr 28. Aging Cell. 2017. PMID: 28455874 Free PMC article.
p53 in Bronchial Club Cells Facilitates Chronic Lung Inflammation by Promoting Senescence.
Sagiv A, Bar-Shai A, Levi N, Hatzav M, Zada L, Ovadya Y, Roitman L, Manella G, Regev O, Majewska J, Vadai E, Eilam R, Feigelson SW, Tsoory M, Tauc M, Alon R, Krizhanovsky V. Sagiv A, et al. Among authors: krizhanovsky v. Cell Rep. 2018 Mar 27;22(13):3468-3479. doi: 10.1016/j.celrep.2018.03.009. Cell Rep. 2018. PMID: 29590616 Free article.
Senolytic elimination of Cox2-expressing senescent cells inhibits the growth of premalignant pancreatic lesions.
Kolodkin-Gal D, Roitman L, Ovadya Y, Azazmeh N, Assouline B, Schlesinger Y, Kalifa R, Horwitz S, Khalatnik Y, Hochner-Ger A, Imam A, Demma JA, Winter E, Benyamini H, Elgavish S, Khatib AA, Meir K, Atlan K, Pikarsky E, Parnas O, Dor Y, Zamir G, Ben-Porath I, Krizhanovsky V. Kolodkin-Gal D, et al. Among authors: krizhanovsky v. Gut. 2022 Feb;71(2):345-355. doi: 10.1136/gutjnl-2020-321112. Epub 2021 Mar 1. Gut. 2022. PMID: 33649045 Free PMC article.
p21 facilitates chronic lung inflammation via epithelial and endothelial cells.
Levi N, Papismadov N, Majewska J, Roitman L, Wigoda N, Eilam R, Tsoory M, Rotkopf R, Ovadya Y, Akiva H, Regev O, Krizhanovsky V. Levi N, et al. Among authors: krizhanovsky v. Aging (Albany NY). 2023 Mar 30;15(7):2395-2417. doi: 10.18632/aging.204622. Epub 2023 Mar 30. Aging (Albany NY). 2023. PMID: 36996500 Free PMC article.
p16-dependent increase of PD-L1 stability regulates immunosurveillance of senescent cells.
Majewska J, Agrawal A, Mayo A, Roitman L, Chatterjee R, Sekeresova Kralova J, Landsberger T, Katzenelenbogen Y, Meir-Salame T, Hagai E, Sopher I, Perez-Correa JF, Wagner W, Maimon A, Amit I, Alon U, Krizhanovsky V. Majewska J, et al. Among authors: krizhanovsky v. Nat Cell Biol. 2024 Aug;26(8):1336-1345. doi: 10.1038/s41556-024-01465-0. Epub 2024 Aug 5. Nat Cell Biol. 2024. PMID: 39103548 Free PMC article.
Senescent cells communicate via intercellular protein transfer.
Biran A, Perelmutter M, Gal H, Burton DG, Ovadya Y, Vadai E, Geiger T, Krizhanovsky V. Biran A, et al. Among authors: krizhanovsky v. Genes Dev. 2015 Apr 15;29(8):791-802. doi: 10.1101/gad.259341.115. Epub 2015 Apr 8. Genes Dev. 2015. PMID: 25854920 Free PMC article.
Cellular Senescence: Defining a Path Forward.
Gorgoulis V, Adams PD, Alimonti A, Bennett DC, Bischof O, Bishop C, Campisi J, Collado M, Evangelou K, Ferbeyre G, Gil J, Hara E, Krizhanovsky V, Jurk D, Maier AB, Narita M, Niedernhofer L, Passos JF, Robbins PD, Schmitt CA, Sedivy J, Vougas K, von Zglinicki T, Zhou D, Serrano M, Demaria M. Gorgoulis V, et al. Among authors: krizhanovsky v. Cell. 2019 Oct 31;179(4):813-827. doi: 10.1016/j.cell.2019.10.005. Cell. 2019. PMID: 31675495 Free article. Review.
Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity.
Kinker GS, Greenwald AC, Tal R, Orlova Z, Cuoco MS, McFarland JM, Warren A, Rodman C, Roth JA, Bender SA, Kumar B, Rocco JW, Fernandes PACM, Mader CC, Keren-Shaul H, Plotnikov A, Barr H, Tsherniak A, Rozenblatt-Rosen O, Krizhanovsky V, Puram SV, Regev A, Tirosh I. Kinker GS, et al. Among authors: krizhanovsky v. Nat Genet. 2020 Nov;52(11):1208-1218. doi: 10.1038/s41588-020-00726-6. Epub 2020 Oct 30. Nat Genet. 2020. PMID: 33128048 Free PMC article.
65 results