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RNA editing modulates the binding of drugs and highly unsaturated fatty acids to the open pore of Kv potassium channels.
Decher N, Streit AK, Rapedius M, Netter MF, Marzian S, Ehling P, Schlichthörl G, Craan T, Renigunta V, Köhler A, Dodel RC, Navarro-Polanco RA, Preisig-Müller R, Klebe G, Budde T, Baukrowitz T, Daut J. Decher N, et al. Among authors: baukrowitz t. EMBO J. 2010 Jul 7;29(13):2101-13. doi: 10.1038/emboj.2010.88. Epub 2010 May 11. EMBO J. 2010. PMID: 20461057 Free PMC article.
The pore structure and gating mechanism of K2P channels.
Piechotta PL, Rapedius M, Stansfeld PJ, Bollepalli MK, Ehrlich G, Andres-Enguix I, Fritzenschaft H, Decher N, Sansom MS, Tucker SJ, Baukrowitz T. Piechotta PL, et al. Among authors: baukrowitz t. EMBO J. 2011 Aug 5;30(17):3607-19. doi: 10.1038/emboj.2011.268. EMBO J. 2011. PMID: 21822218 Free PMC article.
Side pockets provide the basis for a new mechanism of Kv channel-specific inhibition.
Marzian S, Stansfeld PJ, Rapedius M, Rinné S, Nematian-Ardestani E, Abbruzzese JL, Steinmeyer K, Sansom MS, Sanguinetti MC, Baukrowitz T, Decher N. Marzian S, et al. Among authors: baukrowitz t. Nat Chem Biol. 2013 Aug;9(8):507-13. doi: 10.1038/nchembio.1271. Epub 2013 Jun 2. Nat Chem Biol. 2013. PMID: 23728494 Free PMC article.
Sodium permeable and "hypersensitive" TREK-1 channels cause ventricular tachycardia.
Decher N, Ortiz-Bonnin B, Friedrich C, Schewe M, Kiper AK, Rinné S, Seemann G, Peyronnet R, Zumhagen S, Bustos D, Kockskämper J, Kohl P, Just S, González W, Baukrowitz T, Stallmeyer B, Schulze-Bahr E. Decher N, et al. Among authors: baukrowitz t. EMBO Mol Med. 2017 Apr;9(4):403-414. doi: 10.15252/emmm.201606690. EMBO Mol Med. 2017. PMID: 28242754 Free PMC article.
56 results