Varadarajan N - Search Results

1

Single-cell technologies for profiling T cells to enable monitoring of immunotherapies.

An X, Varadarajan N. An X, et al. Among authors: varadarajan n. Curr Opin Chem Eng. 2018 Mar;19:142-152. doi: 10.1016/j.coche.2018.01.003. Epub 2018 Mar 6. Curr Opin Chem Eng. 2018. PMID: 31131208 Free PMC article.

2

Cytotoxic T lymphocytes targeting a conserved SARS-CoV-2 spike epitope are efficient serial killers.

Fathi M, Charley L, Cooper LJN, Varadarajan N, Meyer D. Fathi M, et al. Among authors: varadarajan n. bioRxiv [Preprint]. 2022 Jan 26:2022.01.24.477535. doi: 10.1101/2022.01.24.477535. bioRxiv. 2022. Update in: Biotechniques. 2022 Apr;72(4):113-120. doi: 10.2144/btn-2022-0016. PMID: 35118465 Free PMC article. Updated. Preprint.

3

Quantitative high-throughput single-cell cytotoxicity assay for T cells.

Liadi I, Roszik J, Romain G, Cooper LJ, Varadarajan N. Liadi I, et al. Among authors: varadarajan n. J Vis Exp. 2013 Feb 2;(72):e50058. doi: 10.3791/50058. J Vis Exp. 2013. PMID: 23407457 Free PMC article.

4

Single-cell profiling of dynamic cytokine secretion and the phenotype of immune cells.

An X, Sendra VG, Liadi I, Ramesh B, Romain G, Haymaker C, Martinez-Paniagua M, Lu Y, Radvanyi LG, Roysam B, Varadarajan N. An X, et al. Among authors: varadarajan n. PLoS One. 2017 Aug 24;12(8):e0181904. doi: 10.1371/journal.pone.0181904. eCollection 2017. PLoS One. 2017. PMID: 28837583 Free PMC article.

5

CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression.

Fousek K, Watanabe J, Joseph SK, George A, An X, Byrd TT, Morris JS, Luong A, Martínez-Paniagua MA, Sanber K, Navai SA, Gad AZ, Salsman VS, Mathew PR, Kim HN, Wagner DL, Brunetti L, Jang A, Baker ML, Varadarajan N, Hegde M, Kim YM, Heisterkamp N, Abdel-Azim H, Ahmed N. Fousek K, et al. Among authors: varadarajan n. Leukemia. 2021 Jan;35(1):75-89. doi: 10.1038/s41375-020-0792-2. Epub 2020 Mar 24. Leukemia. 2021. PMID: 32205861 Free PMC article.

6

Single-dose intranasal vaccination elicits systemic and mucosal immunity against SARS-CoV-2.

An X, Martinez-Paniagua M, Rezvan A, Fathi M, Singh S, Biswas S, Pourpak M, Yee C, Liu X, Varadarajan N. An X, et al. Among authors: varadarajan n. bioRxiv [Preprint]. 2020 Jul 23:2020.07.23.212357. doi: 10.1101/2020.07.23.212357. bioRxiv. 2020. Update in: iScience. 2021 Sep 24;24(9):103037. doi: 10.1016/j.isci.2021.103037. PMID: 32743568 Free PMC article. Updated. Preprint.

7

Designed improvement to T-cell immunotherapy by multidimensional single cell profiling.

Bandey IN, Adolacion JRT, Romain G, Paniagua MM, An X, Saeedi A, Liadi I, You Z, Rajanayake RB, Hwu P, Singh H, Cooper LJ, Varadarajan N. Bandey IN, et al. Among authors: varadarajan n. J Immunother Cancer. 2021 Mar;9(3):e001877. doi: 10.1136/jitc-2020-001877. J Immunother Cancer. 2021. PMID: 33722906 Free PMC article.

8

Single-dose intranasal vaccination elicits systemic and mucosal immunity against SARS-CoV-2.

An X, Martinez-Paniagua M, Rezvan A, Sefat SR, Fathi M, Singh S, Biswas S, Pourpak M, Yee C, Liu X, Varadarajan N. An X, et al. Among authors: varadarajan n. iScience. 2021 Sep 24;24(9):103037. doi: 10.1016/j.isci.2021.103037. Epub 2021 Aug 26. iScience. 2021. PMID: 34462731 Free PMC article.

9

Single-Cell Cloning of Breast Cancer Cells Secreting Specific Subsets of Extracellular Vesicles.

Fathi M, Joseph R, Adolacion JRT, Martinez-Paniagua M, An X, Gabrusiewicz K, Mani SA, Varadarajan N. Fathi M, et al. Among authors: varadarajan n. Cancers (Basel). 2021 Aug 31;13(17):4397. doi: 10.3390/cancers13174397. Cancers (Basel). 2021. PMID: 34503207 Free PMC article.

10

Decoding the mechanisms of chimeric antigen receptor (CAR) T cell-mediated killing of tumors: insights from granzyme and Fas inhibition.

Montalvo MJ, Bandey IN, Rezvan A, Wu KL, Saeedi A, Kulkarni R, Li Y, An X, Sefat KMSR, Varadarajan N. Montalvo MJ, et al. Among authors: varadarajan n. Cell Death Dis. 2024 Feb 2;15(2):109. doi: 10.1038/s41419-024-06461-8. Cell Death Dis. 2024. PMID: 38307835 Free PMC article.

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