Parsels JD - Search Results

1

Dose Escalation Trial of the Wee1 Inhibitor Adavosertib (AZD1775) in Combination With Gemcitabine and Radiation for Patients With Locally Advanced Pancreatic Cancer.

Cuneo KC, Morgan MA, Sahai V, Schipper MJ, Parsels LA, Parsels JD, Devasia T, Al-Hawaray M, Cho CS, Nathan H, Maybaum J, Zalupski MM, Lawrence TS. Cuneo KC, et al. Among authors: parsels jd. J Clin Oncol. 2019 Oct 10;37(29):2643-2650. doi: 10.1200/JCO.19.00730. Epub 2019 Aug 9. J Clin Oncol. 2019. PMID: 31398082 Free PMC article. Clinical Trial.

2

Prevention of fluorodeoxyuridine-induced cytotoxicity and DNA damage in HT29 colon carcinoma cells by conditional expression of wild-type p53 phenotype.

Parsels LA, Zellars RC, Loney TL, Parsels JD, Clarke MF, Merchant AK, Lawrence TS, Maybaum J. Parsels LA, et al. Among authors: parsels jd. Mol Pharmacol. 1997 Oct;52(4):600-5. doi: 10.1124/mol.52.4.600. Mol Pharmacol. 1997. PMID: 9380022

3

Mechanism and pharmacological specificity of dUTPase-mediated protection from DNA damage and cytotoxicity in human tumor cells.

Parsels LA, Parsels JD, Wagner LM, Loney TL, Radany EH, Maybaum J. Parsels LA, et al. Among authors: parsels jd. Cancer Chemother Pharmacol. 1998;42(5):357-62. doi: 10.1007/s002800050829. Cancer Chemother Pharmacol. 1998. PMID: 9771948 Free article.

4

Escherichia coli thymidylate synthase expression protects human cells from the cytotoxic effects of 5-fluorodeoxyuridine more effectively than human thymidylate synthase overexpression.

Parsels LA, Kowalski MP, Wagner LM, Parsels JD, Maley F, Maybaum J. Parsels LA, et al. Among authors: parsels jd. Cancer Gene Ther. 2000 Aug;7(8):1179-87. doi: 10.1038/sj.cgt.7700221. Cancer Gene Ther. 2000. PMID: 10975679

5

Cytochrome c depletion upon expression of Bcl-XS.

Fridman JS, Parsels J, Rehemtulla A, Maybaum J. Fridman JS, et al. J Biol Chem. 2001 Feb 9;276(6):4205-10. doi: 10.1074/jbc.M008171200. Epub 2000 Oct 23. J Biol Chem. 2001. PMID: 11044452 Free article.

6

Yeast cytosine deaminase improves radiosensitization and bystander effect by 5-fluorocytosine of human colorectal cancer xenografts.

Kievit E, Nyati MK, Ng E, Stegman LD, Parsels J, Ross BD, Rehemtulla A, Lawrence TS. Kievit E, et al. Cancer Res. 2000 Dec 1;60(23):6649-55. Cancer Res. 2000. PMID: 11118048

7

Regional delivery and selective expression of a high-activity yeast cytosine deaminase in an intrahepatic colon cancer model.

Zhang M, Li S, Nyati MK, DeRemer S, Parsels J, Rehemtulla A, Ensminger WD, Lawrence TS. Zhang M, et al. Cancer Res. 2003 Feb 1;63(3):658-63. Cancer Res. 2003. PMID: 12566311

8

5-fluoro-2'-deoxyuridine-induced cdc25A accumulation correlates with premature mitotic entry and clonogenic death in human colon cancer cells.

Parsels LA, Parsels JD, Tai DC, Coughlin DJ, Maybaum J. Parsels LA, et al. Among authors: parsels jd. Cancer Res. 2004 Sep 15;64(18):6588-94. doi: 10.1158/0008-5472.CAN-03-3040. Cancer Res. 2004. PMID: 15374972

9

Role of checkpoint kinase 1 in preventing premature mitosis in response to gemcitabine.

Morgan MA, Parsels LA, Parsels JD, Mesiwala AK, Maybaum J, Lawrence TS. Morgan MA, et al. Among authors: parsels jd, parsels la. Cancer Res. 2005 Aug 1;65(15):6835-42. doi: 10.1158/0008-5472.CAN-04-2246. Cancer Res. 2005. PMID: 16061666

10

The relationship of premature mitosis to cytotoxicity in response to checkpoint abrogation and antimetabolite treatment.

Morgan MA, Parsels LA, Parsels JD, Lawrence TS, Maybaum J. Morgan MA, et al. Among authors: parsels jd, parsels la. Cell Cycle. 2006 Sep;5(17):1983-8. doi: 10.4161/cc.5.17.3184. Epub 2006 Sep 1. Cell Cycle. 2006. PMID: 16931916 Free article.

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