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The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion.
Li Z, Farias FHG, Dube U, Del-Aguila JL, Mihindukulasuriya KA, Fernandez MV, Ibanez L, Budde JP, Wang F, Lake AM, Deming Y, Perez J, Yang C, Bahena JA, Qin W, Bradley JL, Davenport R, Bergmann K, Morris JC, Perrin RJ, Benitez BA, Dougherty JD, Harari O, Cruchaga C. Li Z, et al. Among authors: deming y. Acta Neuropathol. 2020 Jan;139(1):45-61. doi: 10.1007/s00401-019-02066-0. Epub 2019 Aug 27. Acta Neuropathol. 2020. PMID: 31456032 Free PMC article.
Factors associated with age at tau pathology onset and time from tau onset to dementia.
Heston MB, Teague JP, Cody KA, Deming Y, Ruiz de Chavez E, Morse J, Chin NA, Engelman CD, Chappell RJ, Langhough RE, Gleason CE, Clark LR, Zuelsdorff ML, Betthauser TJ; Alzheimer’s Disease Neuroimaging Initiative. Heston MB, et al. Among authors: deming y. medRxiv [Preprint]. 2025 Mar 13:2025.03.11.25323773. doi: 10.1101/2025.03.11.25323773. medRxiv. 2025. PMID: 40162285 Free PMC article. Preprint.
Gut Microbiome Compositional and Functional Features Associate with Alzheimer's Disease Pathology.
Kang JW, Khatib LA, Heston MB, Dilmore AH, Labus JS, Deming Y, Schimmel L, Blach C, McDonald D, Gonzalez A, Bryant M, Sanders K, Schwartz A, Ulland TK, Johnson SC, Asthana S, Carlsson CM, Chin NA, Blennow K, Zetterberg H, Rey FE; Alzheimer Gut Microbiome Project Consortium; Kaddurah-Daouk R, Knight R, Bendlin BB. Kang JW, et al. Among authors: deming y. medRxiv [Preprint]. 2024 Sep 5:2024.09.04.24313004. doi: 10.1101/2024.09.04.24313004. medRxiv. 2024. PMID: 39281749 Free PMC article. Preprint.
TMEM106B: a strong FTLD disease modifier.
Deming Y, Cruchaga C. Deming Y, et al. Acta Neuropathol. 2014 Mar;127(3):419-22. doi: 10.1007/s00401-014-1249-3. Epub 2014 Feb 1. Acta Neuropathol. 2014. PMID: 24488309 Free PMC article. No abstract available.
A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin.
Deming Y, Xia J, Cai Y, Lord J, Holmans P, Bertelsen S, Holtzman D, Morris JC, Bales K, Pickering EH, Kauwe J, Goate A, Cruchaga C; Alzheimer's Disease Neuroimaging Initiative (ADNI). Deming Y, et al. Neurobiol Aging. 2016 Jan;37:208.e1-208.e9. doi: 10.1016/j.neurobiolaging.2015.09.009. Epub 2015 Sep 25. Neurobiol Aging. 2016. PMID: 26545630 Free PMC article.
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