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Page 1
Overcoming adaptive therapy resistance in AML by targeting immune response pathways.
Melgar K, Walker MM, Jones LM, Bolanos LC, Hueneman K, Wunderlich M, Jiang JK, Wilson KM, Zhang X, Sutter P, Wang A, Xu X, Choi K, Tawa G, Lorimer D, Abendroth J, O'Brien E, Hoyt SB, Berman E, Famulare CA, Mulloy JC, Levine RL, Perentesis JP, Thomas CJ, Starczynowski DT. Melgar K, et al. Among authors: lorimer d. Sci Transl Med. 2019 Sep 4;11(508):eaaw8828. doi: 10.1126/scitranslmed.aaw8828. Sci Transl Med. 2019. PMID: 31484791 Free PMC article.
Crystal structure and biophysical characterization of IspD from Burkholderia thailandensis and Mycobacterium paratuberculosis.
Pierce PG, Hartnett BE, Laughlin TM, Blain JM, Mayclin SJ, Bolejack MJ, Myers JB, Higgins TW, Dranow DM, Sullivan A, Lorimer DD, Edwards TE, Hagen TJ, Horn JR, Myler PJ. Pierce PG, et al. Among authors: lorimer dd. Acta Crystallogr F Struct Biol Commun. 2024 Feb 1;80(Pt 2):43-51. doi: 10.1107/S2053230X24000621. Epub 2024 Jan 31. Acta Crystallogr F Struct Biol Commun. 2024. PMID: 38305785 Free PMC article.
Toward a structome of Acinetobacter baumannii drug targets.
Tillery LM, Barrett KF, Dranow DM, Craig J, Shek R, Chun I, Barrett LK, Phan IQ, Subramanian S, Abendroth J, Lorimer DD, Edwards TE, Van Voorhis WC. Tillery LM, et al. Among authors: lorimer dd. Protein Sci. 2020 Mar;29(3):789-802. doi: 10.1002/pro.3826. Epub 2020 Jan 20. Protein Sci. 2020. PMID: 31930600 Free PMC article.
A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.
Begley DW, Fox D 3rd, Jenner D, Juli C, Pierce PG, Abendroth J, Muruthi M, Safford K, Anderson V, Atkins K, Barnes SR, Moen SO, Raymond AC, Stacy R, Myler PJ, Staker BL, Harmer NJ, Norville IH, Holzgrabe U, Sarkar-Tyson M, Edwards TE, Lorimer DD. Begley DW, et al. Among authors: lorimer dd. Antimicrob Agents Chemother. 2014;58(3):1458-67. doi: 10.1128/AAC.01875-13. Epub 2013 Dec 23. Antimicrob Agents Chemother. 2014. PMID: 24366729 Free PMC article.
Tyrosine aminotransferase from Leishmania infantum: A new drug target candidate.
Moreno MA, Alonso A, Alcolea PJ, Abramov A, de Lacoba MG, Abendroth J, Zhang S, Edwards T, Lorimer D, Myler PJ, Larraga V. Moreno MA, et al. Among authors: lorimer d. Int J Parasitol Drugs Drug Resist. 2014 Jul 30;4(3):347-54. doi: 10.1016/j.ijpddr.2014.06.001. eCollection 2014 Dec. Int J Parasitol Drugs Drug Resist. 2014. PMID: 25516846 Free PMC article.
Crystal structures of Mycobacterial MeaB and MMAA-like GTPases.
Edwards TE, Baugh L, Bullen J, Baydo RO, Witte P, Thompkins K, Phan IQ, Abendroth J, Clifton MC, Sankaran B, Van Voorhis WC, Myler PJ, Staker BL, Grundner C, Lorimer DD. Edwards TE, et al. Among authors: lorimer dd. J Struct Funct Genomics. 2015 Jun;16(2):91-9. doi: 10.1007/s10969-015-9197-2. Epub 2015 Apr 2. J Struct Funct Genomics. 2015. PMID: 25832174 Free PMC article.
Structure of acid deoxyribonuclease.
Varela-Ramirez A, Abendroth J, Mejia AA, Phan IQ, Lorimer DD, Edwards TE, Aguilera RJ. Varela-Ramirez A, et al. Among authors: lorimer dd. Nucleic Acids Res. 2017 Jun 2;45(10):6217-6227. doi: 10.1093/nar/gkx222. Nucleic Acids Res. 2017. PMID: 28369538 Free PMC article.
118 results