Brugge JS - Search Results

1

Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages.

Rosenbluth JM, Schackmann RCJ, Gray GK, Selfors LM, Li CM, Boedicker M, Kuiken HJ, Richardson A, Brock J, Garber J, Dillon D, Sachs N, Clevers H, Brugge JS. Rosenbluth JM, et al. Among authors: brugge js. Nat Commun. 2020 Apr 6;11(1):1711. doi: 10.1038/s41467-020-15548-7. Nat Commun. 2020. PMID: 32249764 Free PMC article.

2

Vav family proteins couple to diverse cell surface receptors.

Moores SL, Selfors LM, Fredericks J, Breit T, Fujikawa K, Alt FW, Brugge JS, Swat W. Moores SL, et al. Among authors: brugge js. Mol Cell Biol. 2000 Sep;20(17):6364-73. doi: 10.1128/MCB.20.17.6364-6373.2000. Mol Cell Biol. 2000. PMID: 10938113 Free PMC article.

3

ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini.

Muthuswamy SK, Li D, Lelievre S, Bissell MJ, Brugge JS. Muthuswamy SK, et al. Among authors: brugge js. Nat Cell Biol. 2001 Sep;3(9):785-92. doi: 10.1038/ncb0901-785. Nat Cell Biol. 2001. PMID: 11533657 Free PMC article.

4

Use of three-dimensional basement membrane cultures to model oncogene-induced changes in mammary epithelial morphogenesis.

Shaw KR, Wrobel CN, Brugge JS. Shaw KR, et al. Among authors: brugge js. J Mammary Gland Biol Neoplasia. 2004 Oct;9(4):297-310. doi: 10.1007/s10911-004-1402-z. J Mammary Gland Biol Neoplasia. 2004. PMID: 15838601 Free PMC article. Review.

5

Modelling glandular epithelial cancers in three-dimensional cultures.

Debnath J, Brugge JS. Debnath J, et al. Among authors: brugge js. Nat Rev Cancer. 2005 Sep;5(9):675-88. doi: 10.1038/nrc1695. Nat Rev Cancer. 2005. PMID: 16148884 Review.

6

Breast cancer-associated PIK3CA mutations are oncogenic in mammary epithelial cells.

Isakoff SJ, Engelman JA, Irie HY, Luo J, Brachmann SM, Pearline RV, Cantley LC, Brugge JS. Isakoff SJ, et al. Among authors: brugge js. Cancer Res. 2005 Dec 1;65(23):10992-1000. doi: 10.1158/0008-5472.CAN-05-2612. Cancer Res. 2005. PMID: 16322248

7

Lumen formation during mammary epithelial morphogenesis: insights from in vitro and in vivo models.

Mailleux AA, Overholtzer M, Brugge JS. Mailleux AA, et al. Among authors: brugge js. Cell Cycle. 2008 Jan 1;7(1):57-62. doi: 10.4161/cc.7.1.5150. Epub 2007 Oct 9. Cell Cycle. 2008. PMID: 18196964 Review.

8

Identification of genes that regulate epithelial cell migration using an siRNA screening approach.

Simpson KJ, Selfors LM, Bui J, Reynolds A, Leake D, Khvorova A, Brugge JS. Simpson KJ, et al. Among authors: brugge js. Nat Cell Biol. 2008 Sep;10(9):1027-38. doi: 10.1038/ncb1762. Nat Cell Biol. 2008. PMID: 19160483

9

Fibroblast growth factor receptor 1-transformed mammary epithelial cells are dependent on RSK activity for growth and survival.

Xian W, Pappas L, Pandya D, Selfors LM, Derksen PW, de Bruin M, Gray NS, Jonkers J, Rosen JM, Brugge JS. Xian W, et al. Among authors: brugge js. Cancer Res. 2009 Mar 15;69(6):2244-51. doi: 10.1158/0008-5472.CAN-08-3398. Epub 2009 Mar 3. Cancer Res. 2009. PMID: 19258500 Free PMC article.

10

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment.

Schafer ZT, Grassian AR, Song L, Jiang Z, Gerhart-Hines Z, Irie HY, Gao S, Puigserver P, Brugge JS. Schafer ZT, et al. Among authors: brugge js. Nature. 2009 Sep 3;461(7260):109-13. doi: 10.1038/nature08268. Epub 2009 Aug 19. Nature. 2009. PMID: 19693011 Free PMC article.

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