Kitajewski JK - Search Results

1

Inhibition of Jagged-Specific Notch Activation Reduces Luteal Angiogenesis and Causes Luteal Hemorrhaging of Hormonally Stimulated Ovaries.

Kofler N, Naiche LA, Zimmerman LD, Kitajewski JK. Kofler N, et al. Among authors: kitajewski jk. ACS Pharmacol Transl Sci. 2019 Sep 4;2(5):325-332. doi: 10.1021/acsptsci.9b00050. eCollection 2019 Oct 11. ACS Pharmacol Transl Sci. 2019. PMID: 32259066 Free PMC article.

2

Notch1 controls macrophage recruitment and Notch signaling is activated at sites of endothelial cell anastomosis during retinal angiogenesis in mice.

Outtz HH, Tattersall IW, Kofler NM, Steinbach N, Kitajewski J. Outtz HH, et al. Blood. 2011 Sep 22;118(12):3436-9. doi: 10.1182/blood-2010-12-327015. Epub 2011 Jul 27. Blood. 2011. PMID: 21795743 Free PMC article.

3

Notch signaling in developmental and tumor angiogenesis.

Kofler NM, Shawber CJ, Kangsamaksin T, Reed HO, Galatioto J, Kitajewski J. Kofler NM, et al. Genes Cancer. 2011 Dec;2(12):1106-16. doi: 10.1177/1947601911423030. Genes Cancer. 2011. PMID: 22866202 Free PMC article.

4

Endothelial Jagged-1 is necessary for homeostatic and regenerative hematopoiesis.

Poulos MG, Guo P, Kofler NM, Pinho S, Gutkin MC, Tikhonova A, Aifantis I, Frenette PS, Kitajewski J, Rafii S, Butler JM. Poulos MG, et al. Cell Rep. 2013 Sep 12;4(5):1022-34. doi: 10.1016/j.celrep.2013.07.048. Epub 2013 Sep 5. Cell Rep. 2013. PMID: 24012753 Free PMC article.

5

NOTCH decoys that selectively block DLL/NOTCH or JAG/NOTCH disrupt angiogenesis by unique mechanisms to inhibit tumor growth.

Kangsamaksin T, Murtomaki A, Kofler NM, Cuervo H, Chaudhri RA, Tattersall IW, Rosenstiel PE, Shawber CJ, Kitajewski J. Kangsamaksin T, et al. Cancer Discov. 2015 Feb;5(2):182-97. doi: 10.1158/2159-8290.CD-14-0650. Epub 2014 Nov 11. Cancer Discov. 2015. PMID: 25387766 Free PMC article.

6

Pericytes are progenitors for coronary artery smooth muscle.

Volz KS, Jacobs AH, Chen HI, Poduri A, McKay AS, Riordan DP, Kofler N, Kitajewski J, Weissman I, Red-Horse K. Volz KS, et al. Elife. 2015 Oct 19;4:e10036. doi: 10.7554/eLife.10036. Elife. 2015. PMID: 26479710 Free PMC article.

7

Combined deficiency of Notch1 and Notch3 causes pericyte dysfunction, models CADASIL, and results in arteriovenous malformations.

Kofler NM, Cuervo H, Uh MK, Murtomäki A, Kitajewski J. Kofler NM, et al. Sci Rep. 2015 Nov 13;5:16449. doi: 10.1038/srep16449. Sci Rep. 2015. PMID: 26563570 Free PMC article.

8

Notch3 signaling promotes tumor cell adhesion and progression in a murine epithelial ovarian cancer model.

Price JC, Azizi E, Naiche LA, Parvani JG, Shukla P, Kim S, Slack-Davis JK, Pe'er D, Kitajewski JK. Price JC, et al. Among authors: kitajewski jk. PLoS One. 2020 Jun 11;15(6):e0233962. doi: 10.1371/journal.pone.0233962. eCollection 2020. PLoS One. 2020. PMID: 32525899 Free PMC article.

9

Neuroblastoma differentiation in vivo excludes cranial tumors.

Treffy RW, Rajan SG, Jiang X, Nacke LM, Malkana UA, Naiche LA, Bergey DE, Santana D, Rajagopalan V, Kitajewski JK, O'Bryan JP, Saxena A. Treffy RW, et al. Among authors: kitajewski jk. Dev Cell. 2021 Oct 11;56(19):2752-2764.e6. doi: 10.1016/j.devcel.2021.09.014. Epub 2021 Oct 4. Dev Cell. 2021. PMID: 34610330 Free PMC article.

10

Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression of endothelial migration.

Swaminathan B, Youn SW, Naiche LA, Du J, Villa SR, Metz JB, Feng H, Zhang C, Kopan R, Sims PA, Kitajewski JK. Swaminathan B, et al. Among authors: kitajewski jk. Sci Rep. 2022 Jan 31;12(1):1655. doi: 10.1038/s41598-022-05666-1. Sci Rep. 2022. PMID: 35102202 Free PMC article.

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