Summa V - Search Results

1

Publisher Correction: 6-Bromoindirubin-3'-oxime intercepts GSK3 signaling to promote and enhance skeletal muscle differentiation affecting miR-206 expression in mice.

Ragozzino E, Brancaccio M, Di Costanzo A, Scalabrì F, Andolfi G, Wanderlingh LG, Patriarca EJ, Minchiotti G, Altamura S, Summa V, Varrone F. Ragozzino E, et al. Among authors: summa v. Sci Rep. 2020 Jun 19;10(1):10232. doi: 10.1038/s41598-020-66768-2. Sci Rep. 2020. PMID: 32561809 Free PMC article.

2

Easy access to α-ketoamides as SARS-CoV-2 and MERS M^pro inhibitors via the PADAM oxidation route.

Pelliccia S, Cerchia C, Esposito F, Cannalire R, Corona A, Costanzi E, Kuzikov M, Gribbon P, Zaliani A, Brindisi M, Storici P, Tramontano E, Summa V. Pelliccia S, et al. Among authors: summa v. Eur J Med Chem. 2022 Dec 15;244:114853. doi: 10.1016/j.ejmech.2022.114853. Epub 2022 Oct 17. Eur J Med Chem. 2022. PMID: 36332546 Free PMC article.

3

Nirmatrelvir treatment of SARS-CoV-2-infected mice blunts antiviral adaptive immune responses.

Fumagalli V, Di Lucia P, Ravà M, Marotta D, Bono E, Grassi S, Donnici L, Cannalire R, Stefanelli I, Ferraro A, Esposito F, Pariani E, Inverso D, Montesano C, Delbue S, Perlman S, Tramontano E, De Francesco R, Summa V, Guidotti LG, Iannacone M. Fumagalli V, et al. Among authors: summa v. EMBO Mol Med. 2023 May 8;15(5):e17580. doi: 10.15252/emmm.202317580. Epub 2023 Mar 22. EMBO Mol Med. 2023. PMID: 36946379 Free PMC article.

4

Approaching a new era for hepatitis C virus therapy: inhibitors of the NS3-4A serine protease and the NS5B RNA-dependent RNA polymerase.

De Francesco R, Tomei L, Altamura S, Summa V, Migliaccio G. De Francesco R, et al. Among authors: summa v. Antiviral Res. 2003 Mar;58(1):1-16. doi: 10.1016/s0166-3542(03)00028-7. Antiviral Res. 2003. PMID: 12719002 Review.

5

Discovery of alpha,gamma-diketo acids as potent selective and reversible inhibitors of hepatitis C virus NS5b RNA-dependent RNA polymerase.

Summa V, Petrocchi A, Pace P, Matassa VG, De Francesco R, Altamura S, Tomei L, Koch U, Neuner P. Summa V, et al. J Med Chem. 2004 Jan 1;47(1):14-7. doi: 10.1021/jm0342109. J Med Chem. 2004. PMID: 14695815

6

The monoethyl ester of meconic acid is an active site inhibitor of HCV NS5B RNA-dependent RNA polymerase.

Pace P, Nizi E, Pacini B, Pesci S, Matassa V, De Francesco R, Altamura S, Summa V. Pace P, et al. Among authors: summa v. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3257-61. doi: 10.1016/j.bmcl.2004.03.087. Bioorg Med Chem Lett. 2004. PMID: 15149686

7

HCV NS5b RNA-dependent RNA polymerase inhibitors: from alpha,gamma-diketoacids to 4,5-dihydroxypyrimidine- or 3-methyl-5-hydroxypyrimidinonecarboxylic acids. Design and synthesis.

Summa V, Petrocchi A, Matassa VG, Taliani M, Laufer R, De Francesco R, Altamura S, Pace P. Summa V, et al. J Med Chem. 2004 Oct 21;47(22):5336-9. doi: 10.1021/jm0494669. J Med Chem. 2004. PMID: 15481971

8

6-Bromoindirubin-3'-oxime intercepts GSK3 signaling to promote and enhance skeletal muscle differentiation affecting miR-206 expression in mice.

Ragozzino E, Brancaccio M, Di Costanzo A, Scalabrì F, Andolfi G, Wanderlingh LG, Patriarca EJ, Minchiotti G, Altamura S, Summa V, Varrone F. Ragozzino E, et al. Among authors: summa v. Sci Rep. 2019 Dec 2;9(1):18091. doi: 10.1038/s41598-019-54574-4. Sci Rep. 2019. PMID: 31792344 Free PMC article.

9

Identification and biological evaluation of a series of 1H-benzo[de]isoquinoline-1,3(2H)-diones as hepatitis C virus NS5B polymerase inhibitors.

Ontoria JM, Rydberg EH, Di Marco S, Tomei L, Attenni B, Malancona S, Martin Hernando JI, Gennari N, Koch U, Narjes F, Rowley M, Summa V, Carroll SS, Olsen DB, De Francesco R, Altamura S, Migliaccio G, Carfì A. Ontoria JM, et al. Among authors: summa v. J Med Chem. 2009 Aug 27;52(16):5217-27. doi: 10.1021/jm900517t. J Med Chem. 2009. PMID: 19877603

10

Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs.

Ontoria JM, Paonessa G, Ponzi S, Ferrigno F, Nizi E, Biancofiore I, Malancona S, Graziani R, Roberts D, Willis P, Bresciani A, Gennari N, Cecchetti O, Monteagudo E, Orsale MV, Veneziano M, Di Marco A, Cellucci A, Laufer R, Altamura S, Summa V, Harper S. Ontoria JM, et al. Among authors: summa v. ACS Med Chem Lett. 2016 Mar 5;7(5):454-9. doi: 10.1021/acsmedchemlett.5b00468. eCollection 2016 May 12. ACS Med Chem Lett. 2016. PMID: 27190592 Free PMC article.

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