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Specific viral RNA drives the SARS CoV-2 nucleocapsid to phase separate.
Iserman C, Roden C, Boerneke M, Sealfon R, McLaughlin G, Jungreis I, Park C, Boppana A, Fritch E, Hou YJ, Theesfeld C, Troyanskaya OG, Baric RS, Sheahan TP, Weeks K, Gladfelter AS. Iserman C, et al. Among authors: gladfelter as. bioRxiv [Preprint]. 2020 Jun 12:2020.06.11.147199. doi: 10.1101/2020.06.11.147199. bioRxiv. 2020. PMID: 32587965 Free PMC article. Preprint.
RNAs kiss and translate in germ granules.
Jalihal AP, Geisterfer ZM, Gladfelter AS. Jalihal AP, et al. Among authors: gladfelter as. Nat Cell Biol. 2024 Nov;26(11):1828-1829. doi: 10.1038/s41556-024-01502-y. Nat Cell Biol. 2024. PMID: 39354133 No abstract available.
mRNA structure determines specificity of a polyQ-driven phase separation.
Langdon EM, Qiu Y, Ghanbari Niaki A, McLaughlin GA, Weidmann CA, Gerbich TM, Smith JA, Crutchley JM, Termini CM, Weeks KM, Myong S, Gladfelter AS. Langdon EM, et al. Among authors: gladfelter as. Science. 2018 May 25;360(6391):922-927. doi: 10.1126/science.aar7432. Epub 2018 Apr 12. Science. 2018. PMID: 29650703 Free PMC article.
Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid.
Iserman C, Roden CA, Boerneke MA, Sealfon RSG, McLaughlin GA, Jungreis I, Fritch EJ, Hou YJ, Ekena J, Weidmann CA, Theesfeld CL, Kellis M, Troyanskaya OG, Baric RS, Sheahan TP, Weeks KM, Gladfelter AS. Iserman C, et al. Among authors: gladfelter as. Mol Cell. 2020 Dec 17;80(6):1078-1091.e6. doi: 10.1016/j.molcel.2020.11.041. Epub 2020 Nov 27. Mol Cell. 2020. PMID: 33290746 Free PMC article.
141 results