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Modeling UBQLN2-mediated neurodegenerative disease in mice: Shared and divergent properties of wild type and mutant UBQLN2 in phase separation, subcellular localization, altered proteostasis pathways, and selective cytotoxicity.
Sharkey LM, Sandoval-Pistorius SS, Moore SJ, Gerson JE, Komlo R, Fischer S, Negron-Rios KY, Crowley EV, Padron F, Patel R, Murphy GG, Paulson HL. Sharkey LM, et al. Among authors: negron rios ky. Neurobiol Dis. 2020 Sep;143:105016. doi: 10.1016/j.nbd.2020.105016. Epub 2020 Jul 10. Neurobiol Dis. 2020. PMID: 32653673 Free PMC article.
Ubiquilin-2 regulates pathological alpha-synuclein.
Sandoval-Pistorius SS, Gerson JE, Liggans N, Ryou JH, Oak K, Li X, Negron-Rios KY, Fischer S, Barsh H, Crowley EV, Skinner ME, Sharkey LM, Barmada SJ, Paulson HL. Sandoval-Pistorius SS, et al. Among authors: negron rios ky. Sci Rep. 2023 Jan 6;13(1):293. doi: 10.1038/s41598-022-26899-0. Sci Rep. 2023. PMID: 36609661 Free PMC article.