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Analysis of Drug Metabolizing Gene Panel in Osteosarcoma Patients Identifies Association Between Variants in SULT1E1, CYP2B6 and CYP4F8 and Methotrexate Levels and Toxicities.
Hurkmans EGE, Klumpers MJ, Vermeulen SH, Hagleitner MM, Flucke U, Schreuder HWB, Gelderblom H, Bras J, Guchelaar HJ, Coenen MJH, Te Loo DMWM. Hurkmans EGE, et al. Among authors: guchelaar hj. Front Pharmacol. 2020 Aug 12;11:1241. doi: 10.3389/fphar.2020.01241. eCollection 2020. Front Pharmacol. 2020. PMID: 32903464 Free PMC article.
Is rectal administration an alternative route for imatinib?
van Erp NP, Oostendorp RL, Guchelaar HJ, Schellens JH, Gelderblom H. van Erp NP, et al. Among authors: guchelaar hj. Cancer Chemother Pharmacol. 2007 Sep;60(4):623-4. doi: 10.1007/s00280-006-0409-0. Epub 2007 Feb 8. Cancer Chemother Pharmacol. 2007. PMID: 17287936 Free article. No abstract available.
Translating pharmacogenomics: challenges on the road to the clinic.
Swen JJ, Huizinga TW, Gelderblom H, de Vries EG, Assendelft WJ, Kirchheiner J, Guchelaar HJ. Swen JJ, et al. Among authors: guchelaar hj. PLoS Med. 2007 Aug;4(8):e209. doi: 10.1371/journal.pmed.0040209. PLoS Med. 2007. PMID: 17696640 Free PMC article. Review.
Pharmacogenetics of EGFR and VEGF inhibition.
Pander J, Gelderblom H, Guchelaar HJ. Pander J, et al. Among authors: guchelaar hj. Drug Discov Today. 2007 Dec;12(23-24):1054-60. doi: 10.1016/j.drudis.2007.10.016. Epub 2007 Nov 26. Drug Discov Today. 2007. PMID: 18061885 Review.
Influence of CYP3A4 inhibition on the steady-state pharmacokinetics of imatinib.
van Erp NP, Gelderblom H, Karlsson MO, Li J, Zhao M, Ouwerkerk J, Nortier JW, Guchelaar HJ, Baker SD, Sparreboom A. van Erp NP, et al. Among authors: guchelaar hj. Clin Cancer Res. 2007 Dec 15;13(24):7394-400. doi: 10.1158/1078-0432.CCR-07-0346. Clin Cancer Res. 2007. PMID: 18094422 Clinical Trial.
480 results