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Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment.
Acharya N, Madi A, Zhang H, Klapholz M, Escobar G, Dulberg S, Christian E, Ferreira M, Dixon KO, Fell G, Tooley K, Mangani D, Xia J, Singer M, Bosenberg M, Neuberg D, Rozenblatt-Rosen O, Regev A, Kuchroo VK, Anderson AC. Acharya N, et al. Among authors: escobar g. Immunity. 2020 Sep 15;53(3):658-671.e6. doi: 10.1016/j.immuni.2020.08.005. Immunity. 2020. PMID: 32937153 Free PMC article.
Spatial determinants of CD8+ T cell differentiation in cancer.
Tooley KA, Escobar G, Anderson AC. Tooley KA, et al. Among authors: escobar g. Trends Cancer. 2022 Aug;8(8):642-654. doi: 10.1016/j.trecan.2022.04.003. Epub 2022 May 5. Trends Cancer. 2022. PMID: 35527216 Free PMC article. Review.
Secretion of a VEGF-blocking scFv enhances CAR T-cell potency.
Supper VM, Donner H, Birocchi F, Bratt A, Escobar G, Kann MC, Park S, Martin G, Korell F, Takei H, Armstrong A, Parker A, Salas-Benito D, Darnell EP, Bailey SR, Kienka T, Philips M, Bouffard A, Goncalves S, Choi BD, Haradhvala NJ, Maus MV, Leick MB. Supper VM, et al. Among authors: escobar g. Cancer Immunol Res. 2025 Jun 2. doi: 10.1158/2326-6066.CIR-24-0876. Online ahead of print. Cancer Immunol Res. 2025. PMID: 40455064
IFN-γ-resistant CD28 CAR T cells demonstrate increased survival, efficacy, and durability in multiple murine tumor models.
Bailey SR, Takei HN, Escobar G, Kann MC, Bouffard AA, Kienka T, Supper VM, Armstrong A, Salas-Benito D, Phillips MK, Birocchi F, Vatsa S, Silva H, Scarfò I, Wehrli M, Grauwet K, Darnell EP, Graham CE, Leick MB, Korell F, Berger TR, Maus MV. Bailey SR, et al. Among authors: escobar g. Sci Transl Med. 2025 Jun 4;17(801):eadp8166. doi: 10.1126/scitranslmed.adp8166. Epub 2025 Jun 4. Sci Transl Med. 2025. PMID: 40465687
Targeted genome editing in human repopulating haematopoietic stem cells.
Genovese P, Schiroli G, Escobar G, Tomaso TD, Firrito C, Calabria A, Moi D, Mazzieri R, Bonini C, Holmes MC, Gregory PD, van der Burg M, Gentner B, Montini E, Lombardo A, Naldini L. Genovese P, et al. Among authors: escobar g. Nature. 2014 Jun 12;510(7504):235-240. doi: 10.1038/nature13420. Epub 2014 May 28. Nature. 2014. PMID: 24870228 Free PMC article.
512 results