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Characterization of organic anion transporting polypeptide (OATP)1B1 and OATP1B3 humanized rat as a translational model to study the pharmacokinetics of OATP1B substrate drugs.
Li Y, Yabut J, Zhang Z, Fauty S, Houle R, Miller H, Zhang NR, Shin MK, Rosahl TW, Zhou HH, Prasad B, Unadkat JD, Chu X. Li Y, et al. Among authors: shin mk. Drug Metab Dispos. 2025 Jun 2;53(7):100101. doi: 10.1016/j.dmd.2025.100101. Online ahead of print. Drug Metab Dispos. 2025. PMID: 40554317
Inhibiting 15-PGDH blocks blood-brain barrier deterioration and protects mice from Alzheimer's disease and traumatic brain injury.
Koh Y, Vázquez-Rosa E, Gao F, Li H, Chakraborty S, Tripathi SJ, Barker S, Bud Z, Bangalore A, Kandjoze UP, León-Alvarado RA, Sridharan PS, Cordova BA, Yu Y, Hyung J, Fang H, Singh S, Katabathula R, LaFramboise T, Kasturi L, Lutterbaugh J, Beard L, Cordova E, Cintrón-Pérez CJ, Franke K, Fragoso MF, Miller E, Indrakumar V, Noel KL, Dhar M, Ajroud K, Zamudio C, Lopes FBTP, Bambakidis E, Zhu X, Wilson B, Flanagan ME, Gefen T, Fujioka H, Fink SP, Desai AB, Dawson D, Williams NS, Kim YK, Ready JM, Paul BD, Shin MK, Markowitz SD, Pieper AA. Koh Y, et al. Among authors: shin mk. Proc Natl Acad Sci U S A. 2025 May 27;122(21):e2417224122. doi: 10.1073/pnas.2417224122. Epub 2025 May 21. Proc Natl Acad Sci U S A. 2025. PMID: 40397680 Free PMC article.
642 results