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Time-resolved single-cell analysis of Brca1 associated mammary tumourigenesis reveals aberrant differentiation of luminal progenitors.
Bach K, Pensa S, Zarocsinceva M, Kania K, Stockis J, Pinaud S, Lazarus KA, Shehata M, Simões BM, Greenhalgh AR, Howell SJ, Clarke RB, Caldas C, Halim TYF, Marioni JC, Khaled WT. Bach K, et al. Among authors: halim tyf. Nat Commun. 2021 Mar 9;12(1):1502. doi: 10.1038/s41467-021-21783-3. Nat Commun. 2021. PMID: 33686070 Free PMC article.
Regulation of regulatory T cells in cancer.
Stockis J, Roychoudhuri R, Halim TYF. Stockis J, et al. Among authors: halim tyf. Immunology. 2019 Jul;157(3):219-231. doi: 10.1111/imm.13064. Epub 2019 May 22. Immunology. 2019. PMID: 31032905 Free PMC article. Review.
ILC2-driven innate immune checkpoint mechanism antagonizes NK cell antimetastatic function in the lung.
Schuijs MJ, Png S, Richard AC, Tsyben A, Hamm G, Stockis J, Garcia C, Pinaud S, Nicholls A, Ros XR, Su J, Eldridge MD, Riedel A, Serrao EM, Rodewald HR, Mack M, Shields JD, Cohen ES, McKenzie ANJ, Goodwin RJA, Brindle KM, Marioni JC, Halim TYF. Schuijs MJ, et al. Among authors: halim tyf. Nat Immunol. 2020 Sep;21(9):998-1009. doi: 10.1038/s41590-020-0745-y. Epub 2020 Aug 3. Nat Immunol. 2020. PMID: 32747815 Free PMC article.
Intratumoral antigen signaling traps CD8+ T cells to confine exhaustion to the tumor site.
Takahashi M, So TY, Chamberlain-Evans V, Hughes R, Yam-Puc JC, Kania K, Ruhle M, Mann T, Schuijs MJ, Coupland P, Naisbitt D, Halim TYF, Lyons PA, Lio P, Roychoudhuri R, Okkenhaug K, Adams DJ, Smith KGC, Jodrell DI, Chapman MA, Thaventhiran JED. Takahashi M, et al. Among authors: halim tyf. Sci Immunol. 2024 May 24;9(95):eade2094. doi: 10.1126/sciimmunol.ade2094. Epub 2024 May 24. Sci Immunol. 2024. PMID: 38787961 Free PMC article.
Cross-talk between ILC2 and Gata3high Tregs locally constrains adaptive type 2 immunity.
Stockis J, Yip T, Moreno-Vicente J, Burton O, Samarakoon Y, Schuijs MJ, Raghunathan S, Garcia C, Luo W, Whiteside SK, Png S, Simpson C, Monk S, Sawle A, Yin K, Barbieri J, Papadopoulos P, Wong H, Rodewald HR, Vyse T, McKenzie ANJ, Cragg MS, Hoare M, Withers DR, Fehling HJ, Roychoudhuri R, Liston A, Halim TYF. Stockis J, et al. Among authors: halim tyf. Sci Immunol. 2024 Jul 19;9(97):eadl1903. doi: 10.1126/sciimmunol.adl1903. Epub 2024 Jul 19. Sci Immunol. 2024. PMID: 39028828
Emerging in vivo tools for ILC2 research.
Halim TYF. Halim TYF. J Exp Med. 2025 Jul 7;222(7):e20250883. doi: 10.1084/jem.20250883. Epub 2025 May 29. J Exp Med. 2025. PMID: 40439585 Free article.
Group 2 innate lymphoid cells in disease.
Halim TY. Halim TY. Int Immunol. 2016 Jan;28(1):13-22. doi: 10.1093/intimm/dxv050. Epub 2015 Aug 25. Int Immunol. 2016. PMID: 26306498 Free PMC article. Review.
30 results