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Hypoxia-Inducible Factor 1 Alpha-Mediated RelB/APOBEC3B Down-regulation Allows Hepatitis B Virus Persistence.
Riedl T, Faure-Dupuy S, Rolland M, Schuehle S, Hizir Z, Calderazzo S, Zhuang X, Wettengel J, Lopez MA, Barnault R, Mirakaj V, Prokosch S, Heide D, Leuchtenberger C, Schneider M, Heßling B, Stottmeier B, Wessbecher IM, Schirmacher P, McKeating JA, Protzer U, Durantel D, Lucifora J, Dejardin E, Heikenwalder M. Riedl T, et al. Among authors: protzer u. Hepatology. 2021 Oct;74(4):1766-1781. doi: 10.1002/hep.31902. Epub 2021 Aug 15. Hepatology. 2021. PMID: 33991110 Free PMC article.
Viral hepatitis and liver cancer.
Ringelhan M, McKeating JA, Protzer U. Ringelhan M, et al. Among authors: protzer u. Philos Trans R Soc Lond B Biol Sci. 2017 Oct 19;372(1732):20160274. doi: 10.1098/rstb.2016.0274. Philos Trans R Soc Lond B Biol Sci. 2017. PMID: 28893941 Free PMC article. Review.
Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques.
Burwitz BJ, Wettengel JM, Mück-Häusl MA, Ringelhan M, Ko C, Festag MM, Hammond KB, Northrup M, Bimber BN, Jacob T, Reed JS, Norris R, Park B, Moller-Tank S, Esser K, Greene JM, Wu HL, Abdulhaqq S, Webb G, Sutton WF, Klug A, Swanson T, Legasse AW, Vu TQ, Asokan A, Haigwood NL, Protzer U, Sacha JB. Burwitz BJ, et al. Among authors: protzer u. Nat Commun. 2017 Dec 15;8(1):2146. doi: 10.1038/s41467-017-01953-y. Nat Commun. 2017. PMID: 29247188 Free PMC article.
A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis.
Wing PA, Davenne T, Wettengel J, Lai AG, Zhuang X, Chakraborty A, D'Arienzo V, Kramer C, Ko C, Harris JM, Schreiner S, Higgs M, Roessler S, Parish JL, Protzer U, Balfe P, Rehwinkel J, McKeating JA. Wing PA, et al. Among authors: protzer u. Life Sci Alliance. 2019 Mar 27;2(2):e201900355. doi: 10.26508/lsa.201900355. Print 2019 Apr. Life Sci Alliance. 2019. PMID: 30918010 Free PMC article.
Interferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20.
Stadler D, Kächele M, Jones AN, Hess J, Urban C, Schneider J, Xia Y, Oswald A, Nebioglu F, Bester R, Lasitschka F, Ringelhan M, Ko C, Chou WM, Geerlof A, van de Klundert MA, Wettengel JM, Schirmacher P, Heikenwälder M, Schreiner S, Bartenschlager R, Pichlmair A, Sattler M, Unger K, Protzer U. Stadler D, et al. Among authors: protzer u. EMBO Rep. 2021 Jun 4;22(6):e49568. doi: 10.15252/embr.201949568. Epub 2021 May 9. EMBO Rep. 2021. PMID: 33969602 Free PMC article.
Long-term hepatitis B virus infection of rhesus macaques requires suppression of host immunity.
Biswas S, Rust LN, Wettengel JM, Yusova S, Fischer M, Carson JN, Johnson J, Wei L, Thode T, Kaadige MR, Sharma S, Agbaria M, Bimber BN, Tu T, Protzer U, Ploss A, Smedley JV, Golomb G, Sacha JB, Burwitz BJ. Biswas S, et al. Among authors: protzer u. Nat Commun. 2022 May 30;13(1):2995. doi: 10.1038/s41467-022-30593-0. Nat Commun. 2022. PMID: 35637225 Free PMC article.
353 results