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Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK.
Chang LS, Oblinger JL, Smith AE, Ferrer M, Angus SP, Hawley E, Petrilli AM, Beauchamp RL, Riecken LB, Erdin S, Poi M, Huang J, Bessler WK, Zhang X, Guha R, Thomas C, Burns SS, Gilbert TSK, Jiang L, Li X, Lu Q, Yuan J, He Y, Dixon SAH, Masters A, Jones DR, Yates CW, Haggarty SJ, La Rosa S, Welling DB, Stemmer-Rachamimov AO, Plotkin SR, Gusella JF, Guinney J, Morrison H, Ramesh V, Fernandez-Valle C, Johnson GL, Blakeley JO, Clapp DW; Synodos for NF2 Consortium. Chang LS, et al. Among authors: welling db. PLoS One. 2021 Jul 15;16(7):e0252048. doi: 10.1371/journal.pone.0252048. eCollection 2021. PLoS One. 2021. PMID: 34264955 Free PMC article.
All in a name: schwannomin versus merlin.
Welling DB, Chang LS. Welling DB, et al. Am J Otol. 2000 Mar;21(2):289. doi: 10.1016/s0196-0709(00)80027-7. Am J Otol. 2000. PMID: 10733201 No abstract available.
cDNA microarray analysis of vestibular schwannomas.
Welling DB, Lasak JM, Akhmametyeva E, Ghaheri B, Chang LS. Welling DB, et al. Otol Neurotol. 2002 Sep;23(5):736-48. doi: 10.1097/00129492-200209000-00022. Otol Neurotol. 2002. PMID: 12218628
Cyclin D(1) and D(3) expression in vestibular schwannomas.
Neff BA, Oberstien E, Lorenz M, Chaudhury AR, Welling DB, Chang LS. Neff BA, et al. Among authors: welling db. Laryngoscope. 2006 Mar;116(3):423-6. doi: 10.1097/01.mlg.0000195076.05466.6c. Laryngoscope. 2006. PMID: 16540902
183 results