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Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug.
Bi J, Khan A, Tang J, Armando AM, Wu S, Zhang W, Gimple RC, Reed A, Jing H, Koga T, Wong IT, Gu Y, Miki S, Yang H, Prager B, Curtis EJ, Wainwright DA, Furnari FB, Rich JN, Cloughesy TF, Kornblum HI, Quehenberger O, Rzhetsky A, Cravatt BF, Mischel PS. Bi J, et al. Among authors: wainwright da. Cell Rep. 2021 Nov 2;37(5):109957. doi: 10.1016/j.celrep.2021.109957. Cell Rep. 2021. PMID: 34731610 Free PMC article.
Management of glioblastoma in elderly patients.
Young JS, Chmura SJ, Wainwright DA, Yamini B, Peters KB, Lukas RV. Young JS, et al. Among authors: wainwright da. J Neurol Sci. 2017 Sep 15;380:250-255. doi: 10.1016/j.jns.2017.07.048. Epub 2017 Aug 1. J Neurol Sci. 2017. PMID: 28870580 Free PMC article. Review.
Unique challenges for glioblastoma immunotherapy-discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. Meeting Report from the 2019 SNO Immuno-Oncology Think Tank.
Chuntova P, Chow F, Watchmaker PB, Galvez M, Heimberger AB, Newell EW, Diaz A, DePinho RA, Li MO, Wherry EJ, Mitchell D, Terabe M, Wainwright DA, Berzofsky JA, Herold-Mende C, Heath JR, Lim M, Margolin KA, Chiocca EA, Kasahara N, Ellingson BM, Brown CE, Chen Y, Fecci PE, Reardon DA, Dunn GP, Liau LM, Costello JF, Wick W, Cloughesy T, Timmer WC, Wen PY, Prins RM, Platten M, Okada H. Chuntova P, et al. Among authors: wainwright da. Neuro Oncol. 2021 Mar 25;23(3):356-375. doi: 10.1093/neuonc/noaa277. Neuro Oncol. 2021. PMID: 33367885 Free PMC article. Review.
Recent developments on immunotherapy for brain cancer.
Wainwright DA, Nigam P, Thaci B, Dey M, Lesniak MS. Wainwright DA, et al. Expert Opin Emerg Drugs. 2012 Jun;17(2):181-202. doi: 10.1517/14728214.2012.679929. Epub 2012 Apr 25. Expert Opin Emerg Drugs. 2012. PMID: 22533851 Free PMC article. Review.
IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma.
Ladomersky E, Zhai L, Lenzen A, Lauing KL, Qian J, Scholtens DM, Gritsina G, Sun X, Liu Y, Yu F, Gong W, Liu Y, Jiang B, Tang T, Patel R, Platanias LC, James CD, Stupp R, Lukas RV, Binder DC, Wainwright DA. Ladomersky E, et al. Among authors: wainwright da. Clin Cancer Res. 2018 Jun 1;24(11):2559-2573. doi: 10.1158/1078-0432.CCR-17-3573. Epub 2018 Mar 2. Clin Cancer Res. 2018. PMID: 29500275 Free PMC article.
Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma.
Ladomersky E, Zhai L, Lauing KL, Bell A, Xu J, Kocherginsky M, Zhang B, Wu JD, Podojil JR, Platanias LC, Mochizuki AY, Prins RM, Kumthekar P, Raizer JJ, Dixit K, Lukas RV, Horbinski C, Wei M, Zhou C, Pawelec G, Campisi J, Grohmann U, Prendergast GC, Munn DH, Wainwright DA. Ladomersky E, et al. Among authors: wainwright da. Clin Cancer Res. 2020 Oct 1;26(19):5232-5245. doi: 10.1158/1078-0432.CCR-19-3874. Epub 2020 Jun 16. Clin Cancer Res. 2020. PMID: 32546647 Free PMC article.
Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies.
Zhai L, Bell A, Ladomersky E, Lauing KL, Bollu L, Sosman JA, Zhang B, Wu JD, Miller SD, Meeks JJ, Lukas RV, Wyatt E, Doglio L, Schiltz GE, McCusker RH, Wainwright DA. Zhai L, et al. Among authors: wainwright da. Front Immunol. 2020 Jun 16;11:1185. doi: 10.3389/fimmu.2020.01185. eCollection 2020. Front Immunol. 2020. PMID: 32612606 Free PMC article. Review.
Targeting CD73 to augment cancer immunotherapy.
Roh M, Wainwright DA, Wu JD, Wan Y, Zhang B. Roh M, et al. Among authors: wainwright da. Curr Opin Pharmacol. 2020 Aug;53:66-76. doi: 10.1016/j.coph.2020.07.001. Epub 2020 Aug 7. Curr Opin Pharmacol. 2020. PMID: 32777746 Free PMC article. Review.
116 results