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The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C.
Pluvinage JV, Sun J, Claes C, Flynn RA, Haney MS, Iram T, Meng X, Lindemann R, Riley NM, Danhash E, Chadarevian JP, Tapp E, Gate D, Kondapavulur S, Cobos I, Chetty S, Pașca AM, Pașca SP, Berry-Kravis E, Bertozzi CR, Blurton-Jones M, Wyss-Coray T. Pluvinage JV, et al. Among authors: tapp e. Sci Transl Med. 2021 Dec;13(622):eabg2919. doi: 10.1126/scitranslmed.abg2919. Epub 2021 Dec 1. Sci Transl Med. 2021. PMID: 34851695 Free PMC article.
CD4+ T cells contribute to neurodegeneration in Lewy body dementia.
Gate D, Tapp E, Leventhal O, Shahid M, Nonninger TJ, Yang AC, Strempfl K, Unger MS, Fehlmann T, Oh H, Channappa D, Henderson VW, Keller A, Aigner L, Galasko DR, Davis MM, Poston KL, Wyss-Coray T. Gate D, et al. Among authors: tapp e. Science. 2021 Nov 12;374(6569):868-874. doi: 10.1126/science.abf7266. Epub 2021 Oct 14. Science. 2021. PMID: 34648304 Free PMC article.
Cerebrospinal fluid immune dysregulation during healthy brain aging and cognitive impairment.
Piehl N, van Olst L, Ramakrishnan A, Teregulova V, Simonton B, Zhang Z, Tapp E, Channappa D, Oh H, Losada PM, Rutledge J, Trelle AN, Mormino EC, Elahi F, Galasko DR, Henderson VW, Wagner AD, Wyss-Coray T, Gate D. Piehl N, et al. Among authors: tapp e. Cell. 2022 Dec 22;185(26):5028-5039.e13. doi: 10.1016/j.cell.2022.11.019. Epub 2022 Dec 13. Cell. 2022. PMID: 36516855 Free PMC article.
A one-step protocol to generate impermeable fluorescent HaloTag substrates for in situ live cell application and super-resolution imaging.
Roßmann K, Sun S, Olesen CH, Kowald M, Tapp E, Pabst U, Bieck M, Birke R, Shields BC, Jeong P, Hong J, Tadross MR, Levitz J, Lehmann M, Lipstein N, Broichhagen J. Roßmann K, et al. Among authors: tapp e. bioRxiv [Preprint]. 2024 Sep 23:2024.09.20.614087. doi: 10.1101/2024.09.20.614087. bioRxiv. 2024. PMID: 39386703 Free PMC article. Preprint.
Basal insulin and cardiovascular and other outcomes in dysglycemia.
ORIGIN Trial Investigators; Gerstein HC, Bosch J, Dagenais GR, Díaz R, Jung H, Maggioni AP, Pogue J, Probstfield J, Ramachandran A, Riddle MC, Rydén LE, Yusuf S. ORIGIN Trial Investigators, et al. N Engl J Med. 2012 Jul 26;367(4):319-28. doi: 10.1056/NEJMoa1203858. Epub 2012 Jun 11. N Engl J Med. 2012. PMID: 22686416 Free article. Clinical Trial.
n-3 fatty acids and cardiovascular outcomes in patients with dysglycemia.
ORIGIN Trial Investigators; Bosch J, Gerstein HC, Dagenais GR, Díaz R, Dyal L, Jung H, Maggiono AP, Probstfield J, Ramachandran A, Riddle MC, Rydén LE, Yusuf S. ORIGIN Trial Investigators, et al. N Engl J Med. 2012 Jul 26;367(4):309-18. doi: 10.1056/NEJMoa1203859. Epub 2012 Jun 11. N Engl J Med. 2012. PMID: 22686415 Free article. Clinical Trial.
86 results