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Beta-amyloid monomers are neuroprotective.
Giuffrida ML, Caraci F, Pignataro B, Cataldo S, De Bona P, Bruno V, Molinaro G, Pappalardo G, Messina A, Palmigiano A, Garozzo D, Nicoletti F, Rizzarelli E, Copani A. Giuffrida ML, et al. J Neurosci. 2009 Aug 26;29(34):10582-7. doi: 10.1523/JNEUROSCI.1736-09.2009. J Neurosci. 2009. PMID: 19710311 Free PMC article.
Monomeric ß-amyloid interacts with type-1 insulin-like growth factor receptors to provide energy supply to neurons.
Giuffrida ML, Tomasello MF, Pandini G, Caraci F, Battaglia G, Busceti C, Di Pietro P, Pappalardo G, Attanasio F, Chiechio S, Bagnoli S, Nacmias B, Sorbi S, Vigneri R, Rizzarelli E, Nicoletti F, Copani A. Giuffrida ML, et al. Front Cell Neurosci. 2015 Aug 7;9:297. doi: 10.3389/fncel.2015.00297. eCollection 2015. Front Cell Neurosci. 2015. PMID: 26300732 Free PMC article.
Corrigendum: Ac-LPFFD-Th: A Trehalose-Conjugated Peptidomimetic as a Strong Suppressor of Amyloid-β Oligomer Formation and Cytotoxicity.
Sinopoli A, Giuffrida A, Tomasello MF, Giuffrida ML, Leone M, Attanasio F, Caraci F, De Bona P, Naletova I, Saviano M, Copani A, Pappalardo G, Rizzarelli E. Sinopoli A, et al. Among authors: giuffrida a, giuffrida ml. Chembiochem. 2016 Oct 17;17(20):1993. doi: 10.1002/cbic.201600502. Epub 2016 Sep 23. Chembiochem. 2016. PMID: 27758068 No abstract available.
Trehalose Conjugates of Silybin as Prodrugs for Targeting Toxic Aβ Aggregates.
García-Viñuales S, Ahmed R, Sciacca MFM, Lanza V, Giuffrida ML, Zimbone S, Romanucci V, Zarrelli A, Bongiorno C, Spinella N, Galati C, Di Fabio G, Melacini G, Milardi D. García-Viñuales S, et al. Among authors: giuffrida ml. ACS Chem Neurosci. 2020 Sep 2;11(17):2566-2576. doi: 10.1021/acschemneuro.0c00232. Epub 2020 Aug 5. ACS Chem Neurosci. 2020. PMID: 32687307
48 results