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Page 1
Towards SINEUP-based therapeutics: Design of an in vitro synthesized SINEUP RNA.
Valentini P, Pierattini B, Zacco E, Mangoni D, Espinoza S, Webster NA, Andrews B, Carninci P, Tartaglia GG, Pandolfini L, Gustincich S. Valentini P, et al. Among authors: webster na. Mol Ther Nucleic Acids. 2022 Feb 2;27:1092-1102. doi: 10.1016/j.omtn.2022.01.021. eCollection 2022 Mar 8. Mol Ther Nucleic Acids. 2022. PMID: 35228902 Free PMC article.
METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation.
Pandolfini L, Barbieri I, Bannister AJ, Hendrick A, Andrews B, Webster N, Murat P, Mach P, Brandi R, Robson SC, Migliori V, Alendar A, d'Onofrio M, Balasubramanian S, Kouzarides T. Pandolfini L, et al. Mol Cell. 2019 Jun 20;74(6):1278-1290.e9. doi: 10.1016/j.molcel.2019.03.040. Epub 2019 Apr 25. Mol Cell. 2019. PMID: 31031083 Free PMC article.
Remodeling of the m6A RNA landscape in the conversion of acute lymphoblastic leukemia cells to macrophages.
Bueno-Costa A, Piñeyro D, García-Prieto CA, Ortiz-Barahona V, Martinez-Verbo L, Webster NA, Andrews B, Kol N, Avrahami C, Moshitch-Moshkovitz S, Rechavi G, Esteller M. Bueno-Costa A, et al. Among authors: webster na. Leukemia. 2022 Aug;36(8):2121-2124. doi: 10.1038/s41375-022-01621-1. Epub 2022 Jun 9. Leukemia. 2022. PMID: 35681051 Free PMC article. No abstract available.
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia.
Yankova E, Blackaby W, Albertella M, Rak J, De Braekeleer E, Tsagkogeorga G, Pilka ES, Aspris D, Leggate D, Hendrick AG, Webster NA, Andrews B, Fosbeary R, Guest P, Irigoyen N, Eleftheriou M, Gozdecka M, Dias JML, Bannister AJ, Vick B, Jeremias I, Vassiliou GS, Rausch O, Tzelepis K, Kouzarides T. Yankova E, et al. Among authors: webster na. Nature. 2021 May;593(7860):597-601. doi: 10.1038/s41586-021-03536-w. Epub 2021 Apr 26. Nature. 2021. PMID: 33902106 Free PMC article.
1,2,4-Triazolo-[1,5-a]pyridine HIF Prolylhydroxylase Domain-1 (PHD-1) Inhibitors With a Novel Monodentate Binding Interaction.
Ahmed S, Ayscough A, Barker GR, Canning HE, Davenport R, Downham R, Harrison D, Jenkins K, Kinsella N, Livermore DG, Wright S, Ivetac AD, Skene R, Wilkens SJ, Webster NA, Hendrick AG. Ahmed S, et al. Among authors: webster na. J Med Chem. 2017 Jul 13;60(13):5663-5672. doi: 10.1021/acs.jmedchem.7b00352. Epub 2017 Jun 24. J Med Chem. 2017. PMID: 28594552
Pharmacological inhibition of METTL3 impacts specific haematopoietic lineages.
Sturgess K, Yankova E, Vijayabaskar MS, Isobe T, Rak J, Kucinski I, Barile M, Webster NA, Eleftheriou M, Hannah R, Gozdecka M, Vassiliou G, Rausch O, Wilson NK, Göttgens B, Tzelepis K. Sturgess K, et al. Among authors: webster na. Leukemia. 2023 Oct;37(10):2133-2137. doi: 10.1038/s41375-023-01965-2. Epub 2023 Jul 19. Leukemia. 2023. PMID: 37464070 Free PMC article. No abstract available.
18 results