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Page 1
Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses.
Rodríguez-Ubreva J, Arutyunyan A, Bonder MJ, Del Pino-Molina L, Clark SJ, de la Calle-Fabregat C, Garcia-Alonso L, Handfield LF, Ciudad L, Andrés-León E, Krueger F, Català-Moll F, Rodríguez-Cortez VC, Polanski K, Mamanova L, van Dongen S, Kiselev VY, Martínez-Saavedra MT, Heyn H, Martín J, Warnatz K, López-Granados E, Rodríguez-Gallego C, Stegle O, Kelsey G, Vento-Tormo R, Ballestar E. Rodríguez-Ubreva J, et al. Nat Commun. 2022 Apr 1;13(1):1779. doi: 10.1038/s41467-022-29450-x. Nat Commun. 2022. PMID: 35365635 Free PMC article.
Multi-omics framework to reveal the molecular determinants of fermentation performance in wine yeast populations.
de Celis M, Ruiz J, Benitez-Dominguez B, Vicente J, Tomasi S, Izquierdo-Gea S, Rozés N, Ruiz-de-Villa C, Gombau J, Zamora F, Barroso-delJesus A, Terron-Camero LC, Andres-Leon E, Santos A, Belda I. de Celis M, et al. Among authors: andres leon e. Microbiome. 2024 Oct 15;12(1):203. doi: 10.1186/s40168-024-01930-w. Microbiome. 2024. PMID: 39407259 Free PMC article.
Exercise and tumor proteome: insights from a neuroblastoma model.
Plaza-Florido A, Gálvez BG, López JA, Santos-Lozano A, Zazo S, Rincón-Castanedo C, Martín-Ruiz A, Lumbreras J, Terron-Camero LC, López-Soto A, Andrés-León E, González-Murillo Á, Rojo F, Ramírez M, Lucia A, Fiuza-Luces C. Plaza-Florido A, et al. Among authors: andres leon e. Physiol Genomics. 2024 Dec 1;56(12):833-844. doi: 10.1152/physiolgenomics.00064.2024. Epub 2024 Sep 23. Physiol Genomics. 2024. PMID: 39311839
Methylome and transcriptome profiling of giant cell arteritis monocytes reveals novel pathways involved in disease pathogenesis and molecular response to glucocorticoids.
Estupiñán-Moreno E, Ortiz-Fernández L, Li T, Hernández-Rodríguez J, Ciudad L, Andrés-León E, Terron-Camero LC, Prieto-González S, Espígol-Frigolé G, Cid MC, Márquez A, Ballestar E, Martín J. Estupiñán-Moreno E, et al. Ann Rheum Dis. 2022 Aug 11;81(9):1290-1300. doi: 10.1136/annrheumdis-2022-222156. Ann Rheum Dis. 2022. PMID: 35705375 Free PMC article.
Single-cell multi-omics analysis of COVID-19 patients with pre-existing autoimmune diseases shows aberrant immune responses to infection.
Barmada A, Handfield LF, Godoy-Tena G, de la Calle-Fabregat C, Ciudad L, Arutyunyan A, Andrés-León E, Hoo R, Porter T, Oszlanczi A, Richardson L, Calero-Nieto FJ, Wilson NK, Marchese D, Sancho-Serra C, Carrillo J, Presas-Rodríguez S, Ramo-Tello C, Ruiz-Sanmartin A, Ferrer R, Ruiz-Rodriguez JC, Martínez-Gallo M, Munera-Campos M, Carrascosa JM, Göttgens B, Heyn H, Prigmore E, Casafont-Solé I, Solanich X, Sánchez-Cerrillo I, González-Álvaro I, Raimondo MG, Ramming A, Martin J, Martínez-Cáceres E, Ballestar E, Vento-Tormo R, Rodríguez-Ubreva J. Barmada A, et al. Eur J Immunol. 2024 Jan;54(1):e2350633. doi: 10.1002/eji.202350633. Epub 2023 Oct 20. Eur J Immunol. 2024. PMID: 37799110 Free article.
Decoding CD4+ T cell transcriptome in giant cell arteritis: Novel pathways and altered cross-talk with monocytes.
Estupiñán-Moreno E, Hernández-Rodríguez J, Li T, Ciudad L, Andrés-León E, Terron-Camero LC, Prieto-González S, Espígol-Frigolé G, Cid MC, Márquez A, Martin J, Ballestar E, Ortiz-Fernández L. Estupiñán-Moreno E, et al. Among authors: andres leon e. J Autoimmun. 2024 Jun;146:103240. doi: 10.1016/j.jaut.2024.103240. Epub 2024 May 15. J Autoimmun. 2024. PMID: 38754238 Free article.
A Strong Dysregulated Myeloid Component in the Epigenetic Landscape of Systemic Sclerosis: An Integrated DNA Methylome and Transcriptome Analysis.
Martínez-López J, Ortiz-Fernandez L, Estupiñán-Moreno E, Kerick M, Andrés-León E, Terron-Camero LC, Carnero-Montoro E, Barturen G, Beretta L, Almeida I; PRECISESADS Clinical Consortium; Alarcón-Riquelme ME, Ballestar E, Acosta-Herrera M, Martín J. Martínez-López J, et al. Among authors: andres leon e. Arthritis Rheumatol. 2025 Apr;77(4):439-449. doi: 10.1002/art.43044. Epub 2024 Dec 12. Arthritis Rheumatol. 2025. PMID: 39468422 Free PMC article.
COVID-19 progression and convalescence in common variable immunodeficiency patients show dysregulated adaptive immune responses and persistent type I interferon and inflammasome activation.
Rodríguez-Ubreva J, Calafell-Segura J, Calvillo CL, Keller B, Ciudad L, Handfield LF, de la Calle-Fabregat C, Godoy-Tena G, Andrés-León E, Hoo R, Porter T, Prigmore E, Hofmann M, Decker A, Martín J, Vento-Tormo R, Warnatz K, Ballestar E. Rodríguez-Ubreva J, et al. Among authors: andres leon e. Nat Commun. 2024 Nov 28;15(1):10344. doi: 10.1038/s41467-024-54732-x. Nat Commun. 2024. PMID: 39609471 Free PMC article.
64 results