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Page 1
Posttranslational modification of microtubules by the MATCAP detyrosinase.
Landskron L, Bak J, Adamopoulos A, Kaplani K, Moraiti M, van den Hengel LG, Song JY, Bleijerveld OB, Nieuwenhuis J, Heidebrecht T, Henneman L, Moutin MJ, Barisic M, Taraviras S, Perrakis A, Brummelkamp TR. Landskron L, et al. Among authors: heidebrecht t. Science. 2022 May 20;376(6595):eabn6020. doi: 10.1126/science.abn6020. Epub 2022 May 20. Science. 2022. PMID: 35482892
Rational Design of Autotaxin Inhibitors by Structural Evolution of Endogenous Modulators.
Keune WJ, Potjewyd F, Heidebrecht T, Salgado-Polo F, Macdonald SJ, Chelvarajan L, Abdel Latif A, Soman S, Morris AJ, Watson AJ, Jamieson C, Perrakis A. Keune WJ, et al. Among authors: heidebrecht t. J Med Chem. 2017 Mar 9;60(5):2006-2017. doi: 10.1021/acs.jmedchem.6b01743. Epub 2017 Feb 16. J Med Chem. 2017. PMID: 28165241 Free article.
Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2 E3 ligase activity to Cdt1.
Hayashi A, Giakoumakis NN, Heidebrecht T, Ishii T, Panagopoulos A, Caillat C, Takahara M, Hibbert RG, Suenaga N, Stadnik-Spiewak M, Takahashi T, Shiomi Y, Taraviras S, von Castelmur E, Lygerou Z, Perrakis A, Nishitani H. Hayashi A, et al. Among authors: heidebrecht t. Life Sci Alliance. 2018 Dec 31;1(6):e201800238. doi: 10.26508/lsa.201800238. eCollection 2018 Dec. Life Sci Alliance. 2018. PMID: 30623174 Free PMC article.
Crystal structure of the tubulin tyrosine carboxypeptidase complex VASH1-SVBP.
Adamopoulos A, Landskron L, Heidebrecht T, Tsakou F, Bleijerveld OB, Altelaar M, Nieuwenhuis J, Celie PHN, Brummelkamp TR, Perrakis A. Adamopoulos A, et al. Among authors: heidebrecht t. Nat Struct Mol Biol. 2019 Jul;26(7):567-570. doi: 10.1038/s41594-019-0254-6. Epub 2019 Jul 1. Nat Struct Mol Biol. 2019. PMID: 31270470
19 results