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A bio-functional polymer that prevents retinal scarring through modulation of NRF2 signalling pathway.
Parikh BH, Liu Z, Blakeley P, Lin Q, Singh M, Ong JY, Ho KH, Lai JW, Bogireddi H, Tran KC, Lim JYC, Xue K, Al-Mubaarak A, Yang B, R S, Regha K, Wong DSL, Tan QSW, Zhang Z, Jeyasekharan AD, Barathi VA, Yu W, Cheong KH, Blenkinsop TA, Hunziker W, Lingam G, Loh XJ, Su X. Parikh BH, et al. Among authors: jeyasekharan ad. Nat Commun. 2022 May 19;13(1):2796. doi: 10.1038/s41467-022-30474-6. Nat Commun. 2022. PMID: 35589753 Free PMC article.
PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis.
Mzoughi S, Fong JY, Papadopoli D, Koh CM, Hulea L, Pigini P, Di Tullio F, Andreacchio G, Hoppe MM, Wollmann H, Low D, Caldez MJ, Peng Y, Torre D, Zhao JN, Uchenunu O, Varano G, Motofeanu CM, Lakshmanan M, Teo SX, Wun CM, Perini G, Tan SY, Ong CB, Al-Haddawi M, Rajarethinam R, Hue SS, Lim ST, Ong CK, Huang D, Ng SB, Bernstein E, Hasson D, Wee KB, Kaldis P, Jeyasekharan A, Dominguez-Sola D, Topisirovic I, Guccione E. Mzoughi S, et al. Nat Commun. 2020 Jul 14;11(1):3520. doi: 10.1038/s41467-020-17064-0. Nat Commun. 2020. PMID: 32665551 Free PMC article.
Spatially-resolved transcriptomics reveal macrophage heterogeneity and prognostic significance in diffuse large B-cell lymphoma.
Liu M, Bertolazzi G, Sridhar S, Lee RX, Jaynes P, Mulder K, Syn N, Hoppe MM, Fan S, Peng Y, Thng J, Chua R, Jayalakshmi, Batumalai Y, De Mel S, Poon L, Chan EHL, Lee J, Hue SS, Chang ST, Chuang SS, Chandy KG, Ye X, Pan-Hammarström Q, Ginhoux F, Chee YL, Ng SB, Tripodo C, Jeyasekharan AD. Liu M, et al. Among authors: jeyasekharan ad. Nat Commun. 2024 Mar 8;15(1):2113. doi: 10.1038/s41467-024-46220-z. Nat Commun. 2024. PMID: 38459052 Free PMC article.
Molecular pathogenic pathways in extranodal NK/T cell lymphoma.
de Mel S, Hue SS, Jeyasekharan AD, Chng WJ, Ng SB. de Mel S, et al. Among authors: jeyasekharan ad. J Hematol Oncol. 2019 Apr 2;12(1):33. doi: 10.1186/s13045-019-0716-7. J Hematol Oncol. 2019. PMID: 30935402 Free PMC article. Review.
PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production.
Srinivas US, Tay NSC, Jaynes P, Anbuselvan A, Ramachandran GK, Wardyn JD, Hoppe MM, Hoang PM, Peng Y, Lim S, Lee MY, Peethala PC, An O, Shendre A, Tan BWQ, Jemimah S, Lakshmanan M, Hu L, Jakhar R, Sachaphibulkij K, Lim LHK, Pervaiz S, Crasta K, Yang H, Tan P, Liang C, Ho L, Khanchandani V, Kappei D, Yong WP, Tan DSP, Bordi M, Campello S, Tam WL, Frezza C, Jeyasekharan AD. Srinivas US, et al. Among authors: jeyasekharan ad. Oncogene. 2022 Mar;41(13):1986-2002. doi: 10.1038/s41388-022-02219-8. Epub 2022 Mar 2. Oncogene. 2022. PMID: 35236967
Super-enhancer-driven TOX2 mediates oncogenesis in Natural Killer/T Cell Lymphoma.
Zhou J, Toh SH, Tan TK, Balan K, Lim JQ, Tan TZ, Xiong S, Jia Y, Ng SB, Peng Y, Jeyasekharan AD, Fan S, Lim ST, Ong CJ, Ong CK, Sanda T, Chng WJ. Zhou J, et al. Among authors: jeyasekharan ad. Mol Cancer. 2023 Apr 10;22(1):69. doi: 10.1186/s12943-023-01767-1. Mol Cancer. 2023. PMID: 37032358 Free PMC article.
81 results