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Early embryonic lethality in complex I associated p.L104P Nubpl mutant mice.
Cheng C, Cleak J, Weiss L, Cater H, Stewart M, Wells S, Columbres RC, Shmara A, Morato Torres CA, Zafar F, Schüle B, Neumann J, Hatchwell E, Kimonis V. Cheng C, et al. Among authors: neumann j. Orphanet J Rare Dis. 2022 Oct 24;17(1):386. doi: 10.1186/s13023-022-02446-y. Orphanet J Rare Dis. 2022. PMID: 36280881 Free PMC article.
A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques.
Tran KM, Kawauchi S, Kramár EA, Rezaie N, Liang HY, Sakr JS, Gomez-Arboledas A, Arreola MA, Cunha CD, Phan J, Wang S, Collins S, Walker A, Shi KX, Neumann J, Filimban G, Shi Z, Milinkeviciute G, Javonillo DI, Tran K, Gantuz M, Forner S, Swarup V, Tenner AJ, LaFerla FM, Wood MA, Mortazavi A, MacGregor GR, Green KN. Tran KM, et al. Among authors: neumann j. Mol Neurodegener. 2023 Feb 17;18(1):12. doi: 10.1186/s13024-023-00598-4. Mol Neurodegener. 2023. PMID: 36803190 Free PMC article.
Interneuron Dysfunction in a New Mouse Model of SCN1A GEFS.
Das A, Zhu B, Xie Y, Zeng L, Pham AT, Neumann JC, Safrina O, Benavides DR, MacGregor GR, Schutte SS, Hunt RF, O'Dowd DK. Das A, et al. eNeuro. 2021 Apr 12;8(2):ENEURO.0394-20.2021. doi: 10.1523/ENEURO.0394-20.2021. Print 2021 Mar-Apr. eNeuro. 2021. PMID: 33658306 Free PMC article.
APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology.
Tran KM, Kwang NE, Butler CA, Gomez-Arboledas A, Kawauchi S, Mar C, Chao D, Barahona RA, Da Cunha C, Tsourmas KI, Shi Z, Wang S, Collins S, Walker A, Shi KX, Alcantara JA, Neumann J, Duong DM, Seyfried NT, Tenner AJ, LaFerla FM, Hohsfield LA, Swarup V, MacGregor GR, Green KN. Tran KM, et al. Among authors: neumann j. Mol Neurodegener. 2025 Jan 22;20(1):9. doi: 10.1186/s13024-024-00793-x. Mol Neurodegener. 2025. PMID: 39844286 Free PMC article.
Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer's disease.
Forner S, Kawauchi S, Balderrama-Gutierrez G, Kramár EA, Matheos DP, Phan J, Javonillo DI, Tran KM, Hingco E, da Cunha C, Rezaie N, Alcantara JA, Baglietto-Vargas D, Jansen C, Neumann J, Wood MA, MacGregor GR, Mortazavi A, Tenner AJ, LaFerla FM, Green KN. Forner S, et al. Among authors: neumann j. Sci Data. 2021 Oct 15;8(1):270. doi: 10.1038/s41597-021-01054-y. Sci Data. 2021. PMID: 34654824 Free PMC article.
The Abca7V1613M variant reduces Aβ generation, plaque load, and neuronal damage.
Butler CA, Mendoza Arvilla A, Milinkeviciute G, Da Cunha C, Kawauchi S, Rezaie N, Liang HY, Javonillo D, Thach A, Wang S, Collins S, Walker A, Shi KX, Neumann J, Gomez-Arboledas A, Henningfield CM, Hohsfield LA, Mapstone M, Tenner AJ, LaFerla FM, Mortazavi A, MacGregor GR, Green KN. Butler CA, et al. Among authors: neumann j. Alzheimers Dement. 2024 Jul;20(7):4914-4934. doi: 10.1002/alz.13783. Epub 2024 Mar 20. Alzheimers Dement. 2024. PMID: 38506634 Free PMC article.
1,826 results