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HSPB8 frameshift mutant aggregates weaken chaperone-assisted selective autophagy in neuromyopathies.
Tedesco B, Vendredy L, Adriaenssens E, Cozzi M, Asselbergh B, Crippa V, Cristofani R, Rusmini P, Ferrari V, Casarotto E, Chierichetti M, Mina F, Pramaggiore P, Galbiati M, Piccolella M, Baets J, Baeke F, De Rycke R, Mouly V, Laurenzi T, Eberini I, Vihola A, Udd B, Weiss L, Kimonis V, Timmerman V, Poletti A. Tedesco B, et al. Among authors: de rycke r. Autophagy. 2023 Aug;19(8):2217-2239. doi: 10.1080/15548627.2023.2179780. Epub 2023 Feb 28. Autophagy. 2023. PMID: 36854646 Free PMC article.
Paneth cell TNF signaling induces gut bacterial translocation and sepsis.
Wallaeys C, Garcia-Gonzalez N, Timmermans S, Vandewalle J, Vanderhaeghen T, De Beul S, Dufoor H, Eggermont M, Moens E, Bosteels V, De Rycke R, Thery F, Impens F, Verbanck S, Lienenklaus S, Janssens S, Blumberg RS, Iwawaki T, Libert C. Wallaeys C, et al. Among authors: de rycke r. Cell Host Microbe. 2024 Oct 9;32(10):1725-1743.e7. doi: 10.1016/j.chom.2024.08.007. Epub 2024 Sep 6. Cell Host Microbe. 2024. PMID: 39243761
Increased TMEM106B levels lead to lysosomal dysfunction which affects synaptic signaling and neuronal health.
Perneel J, Lastra Osua M, Alidadiani S, Peeters N, De Witte L, Heeman B, Manzella S, De Rycke R, Brooks M, Perkerson RB, Calus E, De Coster W, Neumann M, Mackenzie IRA, Van Dam D, Asselbergh B, Ellender T, Zhou X, Rademakers R. Perneel J, et al. Among authors: de rycke r. Mol Neurodegener. 2025 Apr 23;20(1):45. doi: 10.1186/s13024-025-00831-2. Mol Neurodegener. 2025. PMID: 40269985 Free PMC article.
OPENPichia: licence-free Komagataella phaffii chassis strains and toolkit for protein expression.
Claes K, Van Herpe D, Vanluchene R, Roels C, Van Moer B, Wyseure E, Vandewalle K, Eeckhaut H, Yilmaz S, Vanmarcke S, Çıtak E, Fijalkowska D, Grootaert H, Lonigro C, Meuris L, Michielsen G, Naessens J, van Schie L, De Rycke R, De Bruyne M, Borghgraef P, Callewaert N. Claes K, et al. Among authors: de rycke r. Nat Microbiol. 2024 Mar;9(3):864-876. doi: 10.1038/s41564-023-01574-w. Epub 2024 Mar 4. Nat Microbiol. 2024. PMID: 38443579 Free PMC article.
Selective Replacement of Cholesterol with Cationic Amphiphilic Drugs Enables the Design of Lipid Nanoparticles with Improved RNA Delivery.
Bogaert B, Debisschop A, Ehouarne T, Van Eeckhoutte HP, De Volder J, Jacobs A, Pottie E, De Rycke R, Crabbé A, Mestdagh P, Lentacker I, Brusselle GG, Stove C, Verstraelen S, Maes T, Bracke KR, De Smedt SC, Raemdonck K. Bogaert B, et al. Among authors: de rycke r. Nano Lett. 2024 Mar 13;24(10):2961-2971. doi: 10.1021/acs.nanolett.3c03345. Epub 2024 Mar 4. Nano Lett. 2024. PMID: 38477058
178 results