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334 results

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Page 1
Loci for insulin processing and secretion provide insight into type 2 diabetes risk.
Broadaway KA, Yin X, Williamson A, Parsons VA, Wilson EP, Moxley AH, Vadlamudi S, Varshney A, Jackson AU, Ahuja V, Bornstein SR, Corbin LJ, Delgado GE, Dwivedi OP, Fernandes Silva L, Frayling TM, Grallert H, Gustafsson S, Hakaste L, Hammar U, Herder C, Herrmann S, Højlund K, Hughes DA, Kleber ME, Lindgren CM, Liu CT, Luan J, Malmberg A, Moissl AP, Morris AP, Perakakis N, Peters A, Petrie JR, Roden M, Schwarz PEH, Sharma S, Silveira A, Strawbridge RJ, Tuomi T, Wood AR, Wu P, Zethelius B, Baldassarre D, Eriksson JG, Fall T, Florez JC, Fritsche A, Gigante B, Hamsten A, Kajantie E, Laakso M, Lahti J, Lawlor DA, Lind L, März W, Meigs JB, Sundström J, Timpson NJ, Wagner R, Walker M, Wareham NJ, Watkins H, Barroso I, O'Rahilly S, Grarup N, Parker SC, Boehnke M, Langenberg C, Wheeler E, Mohlke KL. Broadaway KA, et al. Among authors: grarup n. Am J Hum Genet. 2023 Feb 2;110(2):284-299. doi: 10.1016/j.ajhg.2023.01.002. Epub 2023 Jan 23. Am J Hum Genet. 2023. PMID: 36693378 Free PMC article.
The Lin28/let-7 axis regulates glucose metabolism.
Zhu H, Shyh-Chang N, Segrè AV, Shinoda G, Shah SP, Einhorn WS, Takeuchi A, Engreitz JM, Hagan JP, Kharas MG, Urbach A, Thornton JE, Triboulet R, Gregory RI; DIAGRAM Consortium; MAGIC Investigators; Altshuler D, Daley GQ. Zhu H, et al. Cell. 2011 Sep 30;147(1):81-94. doi: 10.1016/j.cell.2011.08.033. Cell. 2011. PMID: 21962509 Free PMC article.
A Genome-Wide Association Study of Taste Liking in the Danish Population.
Haydar S, Karlsson CC, Linneberg A, Kårhus LL, Ängquist L, Pedersen O, Bredie W, Hansen T, Grarup N. Haydar S, et al. Among authors: grarup n. J Nutr. 2025 Jun 7:S0022-3166(25)00332-3. doi: 10.1016/j.tjnut.2025.06.001. Online ahead of print. J Nutr. 2025. PMID: 40490135 Free article.
Rare MTNR1B variants causing diminished MT2 signalling associate with elevated HbA1c levels but not with type 2 diabetes.
Sørensen KV, Justesen JM, Ängquist L, Bork-Jensen J, Hartmann B, Jørgensen NR, Rungby J, Sørensen HT, Vaag A, Nielsen JS, Holst JJ, Pedersen O, Linneberg A, Hansen T, Grarup N. Sørensen KV, et al. Among authors: grarup n. Diabetologia. 2025 May;68(5):1016-1030. doi: 10.1007/s00125-025-06381-y. Epub 2025 Mar 10. Diabetologia. 2025. PMID: 40064676 Free PMC article.
Genetic architecture in Greenland is shaped by demography, structure and selection.
Stæger FF, Andersen MK, Li Z, Hjerresen JP, He S, Santander CG, Jensen RT, Rex KF, Thuesen ACB, Hanghøj K, Seiding IH, Jørsboe E, Stinson SE, Rasmussen MS, Balboa RF, Larsen CVL, Bjerregaard P, Schubert M, Meisner J, Linneberg A, Grarup N, Zeggini E, Nielsen R, Jørgensen ME, Hansen T, Moltke I, Albrechtsen A. Stæger FF, et al. Among authors: grarup n. Nature. 2025 Mar;639(8054):404-410. doi: 10.1038/s41586-024-08516-4. Epub 2025 Feb 12. Nature. 2025. PMID: 39939757 Free PMC article.
High Prevalence and Common Forms of Maturity-onset Diabetes of the Young in Greenland.
Thuesen ACB, Backe MB, Garcia-Erill G, Schubert M, Hanghøj KE, Moltke I, Albrechtsen A, Grarup N, Gjesing AP, Jørgensen ME, Hansen T, Pedersen ML. Thuesen ACB, et al. Among authors: grarup n. Can J Diabetes. 2025 Apr;49(3):142-151.e2. doi: 10.1016/j.jcjd.2025.01.002. Epub 2025 Jan 30. Can J Diabetes. 2025. PMID: 39892506 Free article.
Sucrase Isomaltase Dysfunction Reduces Sucrose Intake in Mice and Humans.
Aldiss P, Torices L, Ramne S, Jørgensen ME; Sucrase-Isomaltase Working Group; D'Amato M, Andersen MK. Aldiss P, et al. Gastroenterology. 2025 Mar;168(3):604-607.e3. doi: 10.1053/j.gastro.2024.10.040. Epub 2024 Nov 13. Gastroenterology. 2025. PMID: 39542403 Free article. No abstract available.
NK2R control of energy expenditure and feeding to treat metabolic diseases.
Sass F, Ma T, Ekberg JH, Kirigiti M, Ureña MG, Dollet L, Brown JM, Basse AL, Yacawych WT, Burm HB, Andersen MK, Nielsen TS, Tomlinson AJ, Dmytiyeva O, Christensen DP, Bader L, Vo CT, Wang Y, Rausch DM, Kristensen CK, Gestal-Mato M, In Het Panhuis W, Sjøberg KA, Kernodle S, Petersen JE, Pavlovskyi A, Sandhu M, Moltke I, Jørgensen ME, Albrechtsen A, Grarup N, Babu MM, Rensen PCN, Kooijman S, Seeley RJ, Worthmann A, Heeren J, Pers TH, Hansen T, Gustafsson MBF, Tang-Christensen M, Kilpeläinen TO, Myers MG Jr, Kievit P, Schwartz TW, Hansen JB, Gerhart-Hines Z. Sass F, et al. Among authors: grarup n. Nature. 2024 Nov;635(8040):987-1000. doi: 10.1038/s41586-024-08207-0. Epub 2024 Nov 13. Nature. 2024. PMID: 39537932 Free PMC article.
334 results