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Page 1
Increased cysteine metabolism in PINK1 models of Parkinson's disease.
Travaglio M, Michopoulos F, Yu Y, Popovic R, Foster E, Coen M, Martins LM. Travaglio M, et al. Among authors: coen m. Dis Model Mech. 2023 Jan 1;16(1):dmm049727. doi: 10.1242/dmm.049727. Epub 2023 Jan 25. Dis Model Mech. 2023. PMID: 36695500 Free PMC article.
Mechanistic safety assessment via multi-omic characterisation of systemic pathway perturbations following in vivo MAT2A inhibition.
Fogal V, Michopoulos F, Jarnuczak AF, Hamza GM, Harlfinger S, Davey P, Hulme H, Atkinson SJ, Gabrowski P, Cheung T, Grondine M, Hoover C, Rose J, Bray C, Foster AJ, Askin S, Majumder MM, Fitzpatrick P, Miele E, Macdonald R, Keun HC, Coen M. Fogal V, et al. Among authors: coen m. Arch Toxicol. 2024 Aug;98(8):2589-2603. doi: 10.1007/s00204-024-03771-w. Epub 2024 May 17. Arch Toxicol. 2024. PMID: 38755480 Free PMC article.
Pharmacological inhibition of MERTK induces in vivo retinal degeneration: a multimodal imaging ocular safety assessment.
Hamm G, Maglennon G, Williamson B, Macdonald R, Doherty A, Jones S, Harris J, Blades J, Harmer AR, Barton P, Rawlins PB, Smith P, Winter-Holt J, McMurray L, Johansson J, Fitzpatrick P, McCoull W, Coen M. Hamm G, et al. Among authors: coen m. Arch Toxicol. 2022 Feb;96(2):613-624. doi: 10.1007/s00204-021-03197-8. Epub 2022 Jan 1. Arch Toxicol. 2022. PMID: 34973110 Free PMC article.
Dysregulation of the Lysophosphatidylcholine/Autotaxin/Lysophosphatidic Acid Axis in Acute-on-Chronic Liver Failure Is Associated With Mortality and Systemic Inflammation by Lysophosphatidic Acid-Dependent Monocyte Activation.
Trovato FM, Zia R, Napoli S, Wolfer K, Huang X, Morgan PE, Husbyn H, Elgosbi M, Lucangeli M, Miquel R, Wilson I, Heaton ND, Heneghan MA, Auzinger G, Antoniades CG, Wendon JA, Patel VC, Coen M, Triantafyllou E, McPhail MJ. Trovato FM, et al. Among authors: coen m. Hepatology. 2021 Aug;74(2):907-925. doi: 10.1002/hep.31738. Epub 2021 Jun 15. Hepatology. 2021. PMID: 33908067
Lysophosphatidylcholines modulate immunoregulatory checkpoints in peripheral monocytes and are associated with mortality in people with acute liver failure.
Trovato FM, Zia R, Artru F, Mujib S, Jerome E, Cavazza A, Coen M, Wilson I, Holmes E, Morgan P, Singanayagam A, Bernsmeier C, Napoli S, Bernal W, Wendon J, Miquel R, Menon K, Patel VC, Smith J, Atkinson SR, Triantafyllou E, McPhail MJW. Trovato FM, et al. Among authors: coen m. J Hepatol. 2023 Mar;78(3):558-573. doi: 10.1016/j.jhep.2022.10.031. Epub 2022 Nov 9. J Hepatol. 2023. PMID: 36370949 Free article.
In utero and childhood exposure to tobacco smoke and multi-layer molecular signatures in children.
Vives-Usano M, Hernandez-Ferrer C, Maitre L, Ruiz-Arenas C, Andrusaityte S, Borràs E, Carracedo Á, Casas M, Chatzi L, Coen M, Estivill X, González JR, Grazuleviciene R, Gutzkow KB, Keun HC, Lau CE, Cadiou S, Lepeule J, Mason D, Quintela I, Robinson O, Sabidó E, Santorelli G, Schwarze PE, Siskos AP, Slama R, Vafeiadi M, Martí E, Vrijheid M, Bustamante M. Vives-Usano M, et al. Among authors: coen m. BMC Med. 2020 Aug 19;18(1):243. doi: 10.1186/s12916-020-01686-8. BMC Med. 2020. PMID: 32811491 Free PMC article.
Variability of multi-omics profiles in a population-based child cohort.
Gallego-Paüls M, Hernández-Ferrer C, Bustamante M, Basagaña X, Barrera-Gómez J, Lau CE, Siskos AP, Vives-Usano M, Ruiz-Arenas C, Wright J, Slama R, Heude B, Casas M, Grazuleviciene R, Chatzi L, Borràs E, Sabidó E, Carracedo Á, Estivill X, Urquiza J, Coen M, Keun HC, González JR, Vrijheid M, Maitre L. Gallego-Paüls M, et al. Among authors: coen m. BMC Med. 2021 Jul 22;19(1):166. doi: 10.1186/s12916-021-02027-z. BMC Med. 2021. PMID: 34289836 Free PMC article.
270 results